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Updated: Feb 13, 2026

Measurement of Carotenoids in Perifovea using the Macular Pigment Reflectometer
Published on: January 29, 2020
Recent Analytical Techniques Advances in the Carotenoids and Their Derivatives Determination in Various Matrixes
Daniele Giuffrida1, Paola Donato1, Paola Dugo2,3,4
1Dipartimento di Scienze Biomediche, Odontoiatriche e delle Immagini Morfologiche e Funzionali , University of Messina , Via Consolare Valeria , 98125 Messina , Italy.
Abstract:
In the present perspective, different approaches to the carotenoids analysis will be discussed providing a brief overview of the most advanced both monodimensional and bidimensional liquid chromatographic methodologies applied to the carotenoids analysis, followed by a discussion on the recents advanced supercritical fluid chromatography × liquid chromatography bidimensional approach with photodiode-array and mass spectrometry detection. Moreover a discussion on the online supercritical fluid extraction-supercritical fluid chromatography with tandem mass spectrometry detection applied to the determination of carotenoids and apocarotenoids will also be provided.
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