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Normative Trimester-Specific Thyroid Function Data from India: The State of the Nation.

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  • 1Department of Endocrinology, Mazumdar Shaw Medical Centre, Narayana Health, Bengaluru, Karnataka, India.

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|March 15, 2018
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Summary

Establishing unified Indian data for thyroid stimulating hormone (TSH) is crucial. This review highlights the need for harmonized research to create national TSH ranges for effective screening.

Keywords:
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Area of Science:

  • Endocrinology
  • Reproductive Health
  • Public Health

Background:

  • International guidelines advocate for local trimester-specific thyroid stimulating hormone (TSH) normative data.
  • Currently, a lack of unified Indian data for trimester-specific TSH ranges exists.

Purpose of the Study:

  • To review and discuss the current state of trimester-specific TSH ranges in India.
  • To highlight the need for comprehensive, pan-India TSH normative data.

Main Methods:

  • Systematic collation of recently published TSH data from various Indian centers.
  • Analysis of the strengths and limitations of existing Indian TSH datasets.

Main Results:

  • Available Indian TSH data is fragmented, with varying strengths and limitations.
  • The current data is insufficient to establish unified national normative ranges.

Conclusions:

  • Harmonized, multi-center research is essential to establish national normative TSH data for India.
  • Establishing national TSH ranges will facilitate effective screening and management of thyroid dysfunction in pregnancy.