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Duodenum Cryptococcosis Mimicking Primary Duodenum Cancer on PET/CT Imaging.

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A 73-year-old man with fatigue was initially suspected of duodenal cancer. However, further examination revealed a rare fungal infection, duodenal cryptococcosis, mimicking malignancy on imaging.

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Area of Science:

  • Medical Imaging
  • Infectious Diseases
  • Gastroenterology

Background:

  • A 73-year-old male presented with fatigue and anorexia.
  • A chest CT identified a right lung nodule, prompting further investigation.
  • FDG PET/CT was performed to evaluate the lung nodule's metabolic activity.

Observation:

  • FDG PET/CT demonstrated hypermetabolism in the right lung nodule.
  • Significantly increased FDG uptake was also observed in the duodenal region.
  • Initial interpretation suggested primary duodenal malignancy with metastases.

Findings:

  • Endoscopic examination of the upper gastrointestinal tract was performed.
  • Cultures from the duodenum led to a definitive diagnosis.
  • The patient was diagnosed with duodenal cryptococcosis, a rare fungal infection.

Implications:

  • This case highlights the importance of considering infectious etiologies in suspected gastrointestinal malignancies.
  • FDG PET/CT findings can sometimes mimic cancer, necessitating comprehensive diagnostic approaches.
  • Accurate diagnosis of duodenal cryptococcosis is crucial for appropriate treatment and patient management.