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Behavioral Outbursts in a Child with a Deletion Syndrome, Generalized Epilepsy, Global Developmental Delay, and

Adam H Lewis, Ankur Chugh, Sarah A Sobotka

    Pediatric Annals
    |March 15, 2018
    PubMed

    Insights

    Failure to thrive (FTT) in children with genetic disorders can stem from feeding difficulties, not just the genetic condition itself. Thorough feeding assessments are crucial for effective intervention.

    Area of Science:

    • Developmental Pediatrics
    • Clinical Genetics
    • Nutritional Science

    Background:

    • A 7-year-old girl with 20q13.33 deletion and epilepsy presented with behavioral outbursts and developmental delay.
    • Genetic disorders are often presumed to be the sole cause of failure to thrive (FTT) in affected children.

    Observation:

    • Evaluation revealed failure to thrive (FTT) as the primary cause of behavioral outbursts.
    • A nutritional counseling plan focusing on high-calorie, high-fat, high-protein intake was developed.

    Findings:

    • Motor, communication, and developmental deficits in children with genetic disorders can impair feeding skills.
    • These feeding impairments can induce or worsen FTT, complicating developmental disabilities.

    Implications:

    • Investigating feeding skills and nutritional intake is essential before attributing FTT solely to genetic disorders.
    • Addressing feeding challenges can be a key intervention for FTT in children with genetic conditions and developmental delays.

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