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Updated: Feb 13, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Analysis of Vocal Fold Motion Impairment in Neonates Undergoing Congenital Heart Surgery
Stephanie E Ambrose1,2, Julina Ongkasuwan3,4, Kavita Dedhia1,2
1Department of Otolaryngology-Head and Neck Surgery, Emory University School of Medicine, Atlanta, Georgia.
Insights
Vocal fold motion impairment (VFMI) in neonates after congenital heart surgery (CHS) significantly increases hospital costs, primarily due to longer postprocedure stays. Early detection of VFMI may reduce these costs.
Area of Science:
- Pediatric Cardiology
- Neonatal Surgery
- Otolaryngology
Background:
- Vocal fold motion impairment (VFMI) is a recognized complication following congenital heart surgery (CHS).
- The economic and clinical impact of VFMI in neonates post-CHS remains largely uncharacterized.
Purpose of the Study:
- To assess the association between VFMI and healthcare utilization, specifically cost and postprocedure length of stay (PPLOS).
- To evaluate the impact of VFMI on key clinical outcomes in neonates undergoing CHS.
Main Methods:
- A cross-sectional analysis utilized the 2012 Kids' Inpatient Database (KID).
- Included neonates (0-28 days) who underwent CHS.
- Compared outcomes between neonates with and without VFMI using risk-adjusted models.
Main Results:
- Neonates with VFMI had significantly higher total costs (+$34,000) and PPLOS (+9.1 days).
- The increased cost was primarily attributed to extended PPLOS; VFMI was not a significant cost driver when PPLOS was controlled.
- No significant differences were observed in the odds of pneumonia, gastrostomy, or tracheostomy placement.
Conclusions:
- VFMI following CHS is linked to substantial increases in healthcare costs, driven by prolonged hospital stays.
- These findings support further investigation into standardized VFMI screening protocols post-CHS.
- Early identification and management of VFMI may lead to reduced PPLOS and associated healthcare expenditures.
Importance:
Vocal fold motion impairment (VFMI) is a known risk factor following congenital heart surgery (CHS). The impact of this diagnosis on utilization and outcomes is unknown.
Objective:
To evaluate the cost, postprocedure length of stay (PPLOS), and outcomes for neonates with VFMI after CHS.
Design, Setting, And Participants:
A cross-sectional analysis of the 2012 Kids' Inpatient Database (KID) of neonates who underwent CHS was carried out. The KID is an administrative data set of patients, aged 20 years or younger, and contains data on more than 10 million hospitalizations from 44 states. The KID is limited to inpatient hospitalization and contains discharge summary level of data. Patients were limited to those who were born during the hospitalization and those who were aged 28 days or younger at the time of admission for CHS. A weighted total of 4139 neonates who underwent CHS were identified, of which 3725 survived. The proportion of neonates diagnosed with VFMI was 264 (6.92%) of 3725.
Exposures:
Congenital heart surgery.
Main Outcomes And Measures:
Cost of inpatient hospital stay, postprocedure length of stay, odds of pneumonia, gastrostomy tube placement, and tracheostomy tube placement. Risk-adjusted generalized linear models examined differences in cost and PPLOS between neonates who underwent CHS and were diagnosed with VFMI and those who were not. Risk-adjusted logistic regression compared the odds of selected outcomes (gastrostomy, tracheostomy, pneumonia). Models were weighted to provide national estimates.
Results:
Of 3725 neonates (aged 0-28 days), 2203 (59.1%) were male and 1517 (40.7%) were female. Neonates diagnosed with VFMI had significantly higher total cost by $34 000 (95% CI, 2200-65 000) and PPLOS by 9.1 days (95% CI, 4.6-13.7) compared with those who did not. When PPLOS was included as a covariate in the model for cost, presence of VFMI was no longer significant. There were no differences in odds of pneumonia, gastrostomy, or tracheostomy.
Conclusions And Relevance:
Vocal fold motion impairment after CHS was associated with significant increases in cost owing to increased PPLOS. These findings provide a foundation to further investigate standardized screening for VFMI following CHS; early identification and treatment may decrease cost and PPLOS.
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