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A survival guide for endovascular declotting in dialysis access: procedures, devices, and a statistical analysis of
Panagiotis M Kitrou1, Konstantinos Katsanos1,2, Panagiotis Papadimatos1
1a Department of Interventional Radiology , Patras University Hospital, School of Medicine , Rion , Greece.
Insights
Thrombosis in vascular access is a major complication. A shift towards thrombectomy-dependent procedures and improved devices shows promise for better outcomes in treating thrombosed vascular access.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Nephrology
Background:
- Thrombosis is a significant complication of vascular access.
- Declotting procedures are categorized as thrombolysis-dependent or thrombectomy-dependent.
Purpose of the Study:
- To systematically review and meta-analyze studies on percutaneous treatment of thrombosed vascular access published after 2001.
- To investigate clinical success, postintervention assisted primary patency (PAPP), and influencing factors.
Main Methods:
- Systematic review of 17 studies published after 2001.
- Parametric meta-analysis of clinical data.
Main Results:
- A trend towards thrombectomy-dependent procedures to reduce complications associated with thrombolytic agents.
- Arteriovenous fistulas demonstrate superior PAPP.
- Newer studies indicate non-significant improvements compared to older ones.
- Advancements in angioplasty devices are crucial for declotting success.
Conclusions:
- Thrombectomy-dependent procedures and improved angioplasty devices are key to enhancing outcomes in thrombosed vascular access.
- Arteriovenous fistulas remain a favorable option for patency.
Introduction:
Thrombosis is the most important access-related complication. Several declotting procedures have been suggested falling mainly into two categories; thrombolysis-dependent and thrombectomy-dependent.
Areas Covered:
Seventeen studies after 2001 have been published on percutaneous treatment of thrombosed vascular access. Authors performed a systematic review of these studies together with a parametric meta-analysis of data available investigating clinical success, postintervention assisted primary patency (PAPP) and independent factors that could influence outcome measures.
Expert Commentary:
A shift to thrombectomy-dependent procedures is observed with a view to diminishing complications from the use of thrombolytic agents. Arteriovenous fistulas provide significantly better PAPP, while newer studies show improved, non-significant results compared with older ones. The role of improvement of devices for subsequent angioplasty is of equal importance, if not more, for improved declotting results.
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