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Updated: Feb 13, 2026

Capsular Serotyping of Streptococcus pneumoniae Using the Quellung Reaction
Published on: February 24, 2014
[Streptococcus pneumoniae endocarditis in a child: a case report]
Florencia Escarrá1, Ana G Fedullo1, Natalia Veliz2
1Servicio de Control Epidemiológico e Infectología, Hospital de Pediatría "Juan P. Garrahan", Ciudad Autónoma de Buenos Aires, Argentina.
Insights
Infectious endocarditis (IE) is rare in children, but pneumococcus can cause severe infections. This case highlights the importance of considering IE in children with fever and new heart murmurs.
Area of Science:
- Pediatric Infectious Diseases
- Cardiology
Background:
- Pneumococcus (Streptococcus pneumoniae) remains a prevalent pediatric pathogen despite vaccination.
- Infectious endocarditis (IE) is a rare but serious complication of pneumococcal infections, occurring in 1-7% of cases.
Observation:
- A previously healthy 4-year-old boy presented with fever, new heart murmur, and heart failure.
- Blood cultures confirmed penicillin-susceptible pneumococcus, and echocardiography revealed tricuspid and pulmonary valve vegetations.
Findings:
- The patient received 4 weeks of antibiotic treatment for pneumococcal IE.
- Secondary valve damage necessitated surgical intervention.
Implications:
- Infectious endocarditis should be considered in the differential diagnosis of children with fever and new heart murmurs.
- Pneumococcus should be recognized as a potential cause of severe infections, including IE, in non-hospitalized febrile children.
Introduction:
the incidence of invasive infections caused by pneumococcus (Streptococcus pneumoniae) has declined since generalized vaccination with pneumococcal conjugated vaccine, but it is still a prevalent pathogen in children. Amongst pneumococcal invasive infections, IE (infectious endocarditis) is rare, with an incidence between 1 and 7%.
Case Report:
We describe the case of a previously healthy 4 year old boy, who had received one dose of 10-valent pneumococcal conjugate vaccine who presents with fever, a new heart murmur and heart failure. Blood cultures were posi tive for penicillin susceptible pneumococcus. The transthoracic echocardiogram showed tricuspid and pulmonary valve vegetations. The patient received 4 weeks of antibiotic treatment for pneumo-coccal IE. He presented secondary valve damage that needed surgical treatment.
Conclusions:
IE should be considered as a differential diagnosis of children presenting with fever and a newly diag nosed heart murmur, and pneumococcus as an etiologic agent in non hospitalized febrile patients with severe infections.
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