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[ORAL AND SYSTEMIC SYMPTOMS IN CHILDREN WITH FRUIT ALLERGY]
Taisuke Kato1,2, Naoya Tajima1, Katsumasa Kitamura1
1Department of Allergy, Aichi Children's Healthand Medical Center.
Insights
Pediatric fruit allergies differ based on symptoms. Oral symptoms correlate with multiple fruit allergies and hay fever, while systemic symptoms link to single fruit allergies. Differentiating these is key for management.
Area of Science:
- Pediatric Allergy and Immunology
- Clinical Medicine
- Immunology
Background:
- Fruit allergies are common in children.
- Understanding the clinical presentation is crucial for effective management.
- Differentiating symptom types aids in prognosis and dietary guidance.
Purpose of the Study:
- To clarify the clinical profile of pediatric patients with fruit allergies.
- To differentiate between oral and systemic symptom groups.
- To inform accurate diet guidance, safety management, and prognosis estimation.
Main Methods:
- Retrospective analysis of 265 pediatric outpatients with fruit allergies.
- Inclusion of 32 patients undergoing kiwi or banana oral food challenge (OFC).
- Categorization into oral symptom and systemic symptom groups based on medical records.
Main Results:
- Kiwi was the most frequent allergen (21%).
- Watermelon induced oral symptoms (97%), banana induced systemic reactions (46%).
- Oral symptom group: 54% hay fever, 66% multiple fruit allergies. Systemic symptom group: 24% pollen allergies, 77% single fruit allergy.
Conclusions:
- Distinct clinical profiles exist for oral versus systemic pediatric fruit allergy symptoms.
- Accurate differentiation is vital for personalized dietary advice and allergy management.
- Further research can refine understanding and treatment strategies for pediatric fruit allergies.
Background And Purpose:
The principal aim of this study was to clarify the clinical profile of pediatric patients with fruit allergies.
Subjects And Methods:
We assigned 265 pediatric patients with fruit allergies who were receiving outpatient treatment at Aichi Children's Health and Medical Center and 32 who underwent kiwi or banana oral food chal- lenge (OFC) test to an oral symptom group or a systemic symptom group and retrospectively examined their clinical profiles and prognosis from their medical records.
Results:
The most common cause of fruit allergy was kiwi (139 patients, 21% of all patients). Watermelon had the highest oral symptom induction rate (97%), whereas banana had the highest systemic reaction induction rate (46%). In the oral symptom group, the prevalence of hay fever was 54% and 66% of patients showed aller- gic reaction to multiple fruits. In contrast, in the systemic symptom group, the prevalence of pollen allergies was 24% and 77% of patients showed allergic reaction to a single fruit only. The results revealed that 65% of patients allergic to bananas had infant-onset allergy and seven among 20 patients were confirmed acquisition of tolerability by the OFC test.
Conclusion:
Our data suggest that there is a difference in the clinical profile and disease type between patients with oral symptoms and those with primarily systemic symptoms. It is important to differentiate between these patients for accurate diet guidance, safety management, and prognosis estimation.
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