Related Experiment Video

Updated: Jul 24, 2026

Loop-mediated Isothermal Amplification (LAMP) Assays for the Species-specific Detection of Eimeria that Infect Chickens
06:57

Loop-mediated Isothermal Amplification (LAMP) Assays for the Species-specific Detection of Eimeria that Infect Chickens

Published on: February 20, 2015

'Candidatus Neoehrlichia mikurensis' in Europe

A Portillo1, P Santibáñez1, A M Palomar1

  • 1Center of Rickettsiosis and Arthropod-Borne Diseases, Infectious Diseases Department, Hospital San Pedro-Center of Biomedical Research from La Rioja (CIBIR), La Rioja, Spain.

New Microbes and New Infections
|March 21, 2018
PubMed

Insights

Neoehrlichia mikurensis is an emerging bacterium transmitted by ticks, affecting both immunocompromised and healthy individuals. Early diagnosis requires high suspicion and molecular methods.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Veterinary Medicine

Background:

  • 'Candidatus Neoehrlichia mikurensis' is an uncultured emerging bacterium.
  • It is provisionally classified within the Anaplasmataceae family.
  • Transmitted by Ixodes ricinus ticks in Europe, with rodents as reservoirs.

Purpose of the Study:

  • To summarize the current understanding of 'Candidatus Neoehrlichia mikurensis'.
  • To highlight its distribution, transmission, and clinical significance in humans and animals.
  • To emphasize diagnostic challenges and future research priorities.

Main Methods:

  • Literature review and synthesis of existing data.
  • Epidemiological analysis of Neoehrlichia mikurensis distribution.
  • Clinical case review and diagnostic approach discussion.

Main Results:

  • Neoehrlichia mikurensis is widespread in mammals and birds.
  • It causes inflammatory disease in humans, particularly those with underlying conditions.
  • Asymptomatic infections are recognized in immunocompetent individuals.
  • Diagnosis necessitates high clinical suspicion and molecular detection methods.

Conclusions:

  • 'Candidatus Neoehrlichia mikurensis' represents a significant emerging infectious agent.
  • Accurate diagnosis requires molecular tools and awareness.
  • Prioritizing cultivation and pathogenesis research is crucial for better management.
Keywords:
Dermacentor reticulatusEuropeIxodes ricinuscoinfectiondoxycyclineneoehrlichiosisreservoirticktick-borne diseases‘Candidatus Neoehrlichia mikurensis’

More Related Videos

Merkel Cell Polyomavirus Infection and Detection13:45

Merkel Cell Polyomavirus Infection and Detection

Published on: February 7, 2019

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae06:04

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae

Published on: February 24, 2023

Related Concept Videos

Bacterial Phylum Spirochaetes01:30

Bacterial Phylum Spirochaetes

Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased by a...
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
Diversity of Protists I01:15

Diversity of Protists I

Excavata is a diverse group of protists that includes both chemoorganotrophic and phototrophic species, with some thriving in anaerobic environments. Among the key groups within Excavata are diplomonads and parabasalids, which are flagellated protists that lack mitochondria and chloroplasts. These microorganisms typically inhabit anoxic environments, such as the intestines of animals, where they exist either symbiotically or as parasites, relying on fermentation for energy production. Some...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Rabies01:28

Rabies

Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...