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Related Concept Videos

Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

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Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
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Pathophysiology of Heart Failure01:17

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Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
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Heart Failure I: Introduction01:27

Heart Failure I: Introduction

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Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
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Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

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Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
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Heart Failure Drugs: Diuretics01:22

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Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...
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Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

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Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
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Updated: Feb 13, 2026

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
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[Chronic heart failure and depression].

C Herrmann-Lingen1,2

  • 1Klinik für Psychosomatische Medizin und Psychotherapie, Universitätsmedizin Göttingen, Georg-August-Universität, von-Siebold-Str. 5, 37099, Göttingen, Deutschland. cherrma@gwdg.de.

Der Internist
|March 21, 2018
PubMed
Summary
This summary is machine-generated.

Depression frequently co-occurs with heart failure, impacting quality of life. While psychotherapy shows promise, current evidence doesn't support specific antidepressant treatments for heart failure patients beyond standard care.

Keywords:
Adaptation, psychologicalAntidepressive agentsCognitive behavioral therapyComorbidityQuality of life

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Area of Science:

  • Cardiology
  • Psychiatry
  • Psychocardiology

Background:

  • Depression is a common comorbidity in chronic heart failure (CHF).
  • It can be both a consequence of CHF and a contributing factor to its progression and poor prognosis.

Purpose of the Study:

  • Investigate the links between heart failure and depression.
  • Examine psychophysiological and behavioral mechanisms involved.
  • Assess depression's impact on quality of life in CHF patients and review therapies.

Main Methods:

  • A narrative literature review was conducted.

Main Results:

  • Psychophysiological and behavioral factors mediate the association between depression and CHF.
  • Comorbid depression significantly reduces health-related quality of life.
  • Exercise and cognitive behavioral therapy offer partial improvement; antidepressant efficacy is unproven in CHF.

Conclusions:

  • Current guidelines suggest identifying and treating depression in CHF patients.
  • No specific treatments beyond standard CHF care, lifestyle changes, and patient-centered care are strongly supported.
  • Psychotherapy, particularly cognitive behavioral therapy, is recommended. Specialized psychocardiological inpatient programs are available in Germany.