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A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse

A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse

Published on: October 24, 2017

Polyarteritis Nodosa in Pregnancy.

Laura Damian^1,2, Cristina Pamfil^2,3, Marius Fodor⁴

¹Department of Rheumatology, Emergency Clinical County Hospital, Cluj-Napoca, Romania.

Ochsner Journal

|March 22, 2018

Summary

This summary is machine-generated.

Polyarteritis nodosa (PAN) rarely occurs during pregnancy. A case of peripartum PAN in a twin pregnancy highlights the importance of physical examination for diagnosing rare diseases.

Keywords:

Polyarteritis nodosa pregnancy pregnancy outcome vasculitis

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Area of Science:

Rheumatology
Obstetrics
Dermatology

Background:

Polyarteritis nodosa (PAN) is a rare systemic vasculitis, typically affecting middle-aged males.
Pregnancy onset of PAN is exceptionally rare, posing diagnostic challenges.

Observation:

A case of peripartum PAN is presented in a patient with a twin pregnancy, conceived via ovarian stimulation for infertility.
The patient presented with nonspecific symptoms mimicking puerperal infection, delaying diagnosis.
A subcutaneous nodule on the forearm, confirmed by histopathology, was key to diagnosis.

Findings:

Successful treatment with pulse methylprednisolone and intravenous cyclophosphamide led to prompt recovery.
The twin pregnancy outcome was favorable for the infants' health.

Implications:

This case underscores the critical role of thorough physical examination in identifying rare conditions like PAN.
Early diagnosis and prompt treatment are crucial for managing PAN during pregnancy.