Related Experiment Video
Updated: Feb 13, 2026
Standard Operating Procedure for Lyssavirus Surveillance of the Bat Population in Taiwan
Published on: August 27, 2019
Molecular characteristics of mumps viruses isolated in Taiwan from 2006 to 2016
Wen-Yueh Cheng1, Ming-Tsan Liu1
1Centers for Disease Control, Ministry of Health and Welfare, Taiwan, R.O.C. No. 161, Kun-Yang Street, Taipei, 11561, Taiwan, ROC.
Abstract:
Sixteen mumps virus (MuV) sequences collected in Taiwan between 2006 and 2016 were characterized as genotype F (n = 1), G (n = 7), H (n = 4), J (n = 2), and K (n = 2). Mumps genotype F strain was imported from China in 2008 which was in accordance with the epidemic genotype in China. The Philippines was indicated as export country of three genotype H strains in 2007-2010 and Vietnam as export country of one genotype K strain in 2016 that matched with genotypes described in previous reports. Four strains of genotype G were imported from Japan, Thailand, Malaysia and Myanmar individually indicated that genotype G spreads widely in Asia as well as in the global. In this study, mumps strains of genotype G was first reported in relation to import from Malaysia and Myanmar. Furthermore, Indonesia was referred to export MuV of genotype J in 2007 for the first time. Molecular genotyping benefits the differentiation of circulating mumps viruses and can be used to investigate the transmission pathways. The dynamic genotypes of imported cases revealed the epidemic genotypes in nearby countries.
Insights
Molecular genotyping of mumps virus (MuV) in Taiwan revealed diverse genotypes F, G, H, J, and K between 2006-2016. Imported strains highlighted regional transmission patterns and epidemic genotypes in neighboring Asian countries.
Area of Science:
- Virology
- Epidemiology
- Molecular Biology
Background:
- Mumps virus (MuV) circulates globally, with genetic diversity influencing transmission dynamics.
- Understanding the genotypes of circulating MuV is crucial for effective public health surveillance and control strategies.
Purpose of the Study:
- To characterize the genetic diversity of mumps virus (MuV) strains detected in Taiwan between 2006 and 2016.
- To investigate the origins and transmission pathways of imported MuV genotypes in Taiwan.
Main Methods:
- Phylogenetic analysis of sixteen mumps virus (MuV) sequences collected in Taiwan.
- Genotyping of MuV strains based on established classification systems.
Main Results:
- Sixteen MuV sequences were identified, belonging to genotypes F (n=1), G (n=7), H (n=4), J (n=2), and K (n=2).
- Imported strains indicated origins from China (genotype F), the Philippines (genotype H), Vietnam (genotype K), Japan, Thailand, Malaysia, and Myanmar (genotype G), and Indonesia (genotype J).
- Genotype G strains, particularly those linked to Malaysia and Myanmar, were reported for the first time in this study, underscoring the wide spread of this genotype in Asia.
Conclusions:
- Molecular genotyping effectively differentiates circulating mumps viruses and aids in tracing transmission routes.
- The dynamic genotypes of imported mumps cases in Taiwan reflect the prevalent genotypes in neighboring countries, providing insights into regional epidemiology.
Related Concept Videos
01:23Characteristics of Life
00:50What are Viruses?
01:20Characteristics of Fluids
01:31Characteristics of Fluids
Fluids, which include both liquids and gases, are substances that deform continuously under shearing stress. For example, water and oil are liquids with molecules that can...
01:17Characteristics of BJT
For input characteristics, the base-emitter voltage is varied, maintaining a constant collector-emitter voltage. This setup reveals a Shockley-type dependence of the collector current on...
01:21Characteristics of JFET
The core of a JFET's operation is controlling drain current by modulating the gate-source voltage. When the drain and gate voltage are set to zero, the JFET exhibits no net current flow, representing a state of equilibrium. The drain current increases linearly as the...