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Updated: Feb 13, 2026

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Abnormal Functional Connectivity Between Default and Salience Networks in Pediatric Bipolar Disorder

Melissa P Lopez-Larson1, Lubdha M Shah2, Howard R Weeks3

  • 1The Brain Institute, U.S. Department of Veterans Affairs, Salt Lake City, Utah; University of Utah, University of Utah Medical School, U.S. Department of Veterans Affairs, Salt Lake City, Utah.

Biological Psychiatry. Cognitive Neuroscience and Neuroimaging
|March 22, 2018
PubMed
Summary

Pediatric bipolar disorder (PBD) is linked to altered brain connectivity in youth. Specifically, PBD affects the anticorrelation between default mode and salience networks during adolescent development.

Keywords:
AttentionBipolarBrain networksDefault modeResting stateSalience

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