Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Polymers02:34

Polymers

41.2K
The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the...
41.2K
Polymers02:34

Polymers

23.4K
23.4K
Protein Folding01:22

Protein Folding

128.2K
Overview
128.2K
Protein Folding01:25

Protein Folding

11.6K
Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation, critical to its biological function. Interactions between its constituent amino acids guide protein folding, and hence the protein structure is primarily dependent on its amino acid sequence.
Protein Structure Is Critical to Its Biological Function
Proteins perform a wide range of biological functions such as catalyzing chemical reactions, providing...
11.6K
Electron Transport Chains01:28

Electron Transport Chains

113.1K
The final stage of cellular respiration is oxidative phosphorylation that consists of two steps: the electron transport chain and chemiosmosis. The electron transport chain is a set of proteins found in the inner mitochondrial membrane in eukaryotic cells. Its primary function is to establish a proton gradient that can be used during chemiosmosis to produce ATP and generate electron carriers, such as NAD+ and FAD, that are used in glycolysis and the citric acid cycle.
The ETC is comprised of...
113.1K
Molecular Chaperones and Protein Folding03:00

Molecular Chaperones and Protein Folding

19.9K
The native conformation of a protein is formed by interactions between the side chains of its constituent amino acids. When the amino acids cannot form these interactions, the protein cannot fold by itself and needs chaperones. Notably, chaperones do not relay any additional information required for the folding of polypeptides; the native conformation of a protein is determined solely by its amino acid sequence. Chaperones catalyze protein folding without being a part of the folded protein.
The...
19.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Macromolecules with Tunable Fluorescence via Photochemical Step-Growth Polymerization.

ACS macro letters·2026
Same author

Understanding Wavelength-Dependent Photopolymerizations via Nano-Second Resolved Transient Spectroscopy.

Journal of the American Chemical Society·2026
Same author

Following the formation of single-chain nanoparticles generated by interblock crosslinking within diblock copolymers: a Monte Carlo simulation study with adjustable interaction strength between the blocks.

Soft matter·2026
Same author

Wavelength-Dependent 3D Printing: Introducing 3D Printed Action Plots.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Bottlebrush Polymers for Multiphoton 3D Laser Printing.

ACS macro letters·2026
Same author

Wavelength-resolved heterodimer [2 + 2] photocycloadditions for reversible surface grafting.

Chemical science·2026
Same journal

3-Methyleneazetidine: a versatile building block for functional and post-modifiable polysulfonamides.

Chemical communications (Cambridge, England)·2026
Same journal

Synthesis of divalent galactosyl and fucosyl spiropyran derivatives for the targeted inhibition of bacterial biofilms.

Chemical communications (Cambridge, England)·2026
Same journal

Emergent cytotoxicity and mitochondrial alterations induced by a heterobimetallic Re(I)/Au(I) complex.

Chemical communications (Cambridge, England)·2026
Same journal

Cyanoacetylation of amines <i>via</i> a traceless cyanoacetyl radical: synthetic access to teriflunomide.

Chemical communications (Cambridge, England)·2026
Same journal

Loading layered double hydroxide nanoarray catalysts on a micro-curved substrate for kinetics-favorable water electrolysis reaction.

Chemical communications (Cambridge, England)·2026
Same journal

Bridging <i>in situ</i> measurements and practical conditions through gas-liquid management for CO/CO<sub>2</sub> reduction.

Chemical communications (Cambridge, England)·2026
See all related articles

Related Experiment Video

Updated: Feb 13, 2026

Atom Transfer Radical Polymerization of Functionalized Vinyl Monomers Using Perylene as a Visible Light Photocatalyst
06:49

Atom Transfer Radical Polymerization of Functionalized Vinyl Monomers Using Perylene as a Visible Light Photocatalyst

Published on: April 22, 2016

12.4K

Folding polymer chains with visible light.

Carolin Heiler1, Simon Bastian2, Paul Lederhose1

  • 1Macromolecular Architectures, Institut für Technische Chemie und Polymerchemie, Karlsruhe Institute of Technology (KIT), Engesserstr. 18, 76128 Karlsruhe, Germany. christopher.barner-kowollik@kit.edu eva.blasco@kit.edu and School of Chemistry, Physics and Mechanical Engineering, Queensland University of Technology (QUT), Queensland 4000, Australia. christopher.barnerkowollik@qut.edu.au.

Chemical Communications (Cambridge, England)
|March 22, 2018
PubMed
Summary
This summary is machine-generated.

Researchers developed a new, mild method using visible light to fold single polymer chains into nanoparticles. This light-driven approach utilizes versatile tetrazole chemistry for efficient polymer folding.

More Related Videos

Inactivation of Pathogens via Visible-Light Photolysis of Riboflavin-5&#8242;-Phosphate
08:25

Inactivation of Pathogens via Visible-Light Photolysis of Riboflavin-5′-Phosphate

Published on: April 6, 2022

2.3K
The Synergistic Effect of Visible Light and Gentamycin on Pseudomona aeruginosa Microorganisms
05:57

The Synergistic Effect of Visible Light and Gentamycin on Pseudomona aeruginosa Microorganisms

Published on: July 2, 2013

13.8K

Related Experiment Videos

Last Updated: Feb 13, 2026

Atom Transfer Radical Polymerization of Functionalized Vinyl Monomers Using Perylene as a Visible Light Photocatalyst
06:49

Atom Transfer Radical Polymerization of Functionalized Vinyl Monomers Using Perylene as a Visible Light Photocatalyst

Published on: April 22, 2016

12.4K
Inactivation of Pathogens via Visible-Light Photolysis of Riboflavin-5&#8242;-Phosphate
08:25

Inactivation of Pathogens via Visible-Light Photolysis of Riboflavin-5′-Phosphate

Published on: April 6, 2022

2.3K
The Synergistic Effect of Visible Light and Gentamycin on Pseudomona aeruginosa Microorganisms
05:57

The Synergistic Effect of Visible Light and Gentamycin on Pseudomona aeruginosa Microorganisms

Published on: July 2, 2013

13.8K

Area of Science:

  • Polymer Chemistry
  • Materials Science
  • Photochemistry

Background:

  • Single-chain polymer nanoparticles (SCNPs) are crucial in various applications, but their synthesis often requires harsh conditions.
  • Developing mild and efficient methods for SCNP formation is essential for broader applicability.

Purpose of the Study:

  • To introduce a novel, mild, and efficient method for inducing the folding of single polymer chains into nanoparticles using visible light.
  • To demonstrate the versatility of this light-driven approach through multiple folding mechanisms.

Main Methods:

  • Utilizing visible light as the driving force for polymer folding.
  • Exploiting tetrazole chemistry, including nitrile imine-mediated tetrazole-ene cycloaddition (NITEC), nitrile imine carboxylic acid ligation (NICAL), and nitrile imine self-dimerization.
  • Investigating the folding of single polymer chains into compact nanoparticles.

Main Results:

  • Successfully demonstrated a mild and efficient visible light-induced folding of single polymer chains.
  • Showcased the versatility of the method through three distinct tetrazole-based folding mechanisms.
  • Achieved polymer folding into compact nanoparticles under mild conditions.

Conclusions:

  • The developed visible light-driven method offers a mild and efficient pathway for SCNP synthesis.
  • The employed tetrazole chemistry provides versatile options for controlling polymer folding.
  • This approach represents a significant advancement in light-induced polymer self-assembly.