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Direct Oral Anticoagulants in Dental Patients Including the Frail Elderly Population
Hui Yin Lim1,2, Prahlad Ho3,4
1Department of Haematology, Northern Health, 185 Cooper Street, Epping VIC 3076, Australia. huiyin.lim@austin.org.au.
Abstract:
Direct oral anticoagulants (DOACs) have led to a paradigm shift in the field of anticoagulation, providing safe and convenient anticoagulation without the need for regular blood testing. Currently, there are three major DOACs available-Factor Xa inhibitors (apixaban and rivaroxaban) and direct thrombin inhibitors (dabigatran)-that are available for use in atrial fibrillation and venous thromboembolism. While these agents have been shown to be as effective as warfarin, with a similar or better bleeding profile, there remains some concern of the use of these drugs in vulnerable populations, such as the frail elderly patients; particularly since reversal agents and drug monitoring are not routinely available. We aim to provide a review of the use of DOACs and the impact of DOACs on dental treatment in the elderly population.
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