Related Experiment Video
Updated: Feb 13, 2026
06:45
Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems
Published on: May 2, 2025
895
Negative Pressure Wound Therapy in Maxillofacial Applications.
Adam J Mellott1, David S Zamierowski2, Brian T Andrews3
1Department of Plastic Surgery, University of Kansas Medical Center, Kansas City, KS 66160, USA. amellott@kumc.edu.
Dentistry Journal
|March 23, 2018
Summary
Negative pressure wound therapy (NPWT) accelerates wound healing. Adapting NPWT for maxillofacial applications could improve closure in complex head and neck wounds, despite sealing challenges.
Area of Science:
- Wound healing
- Surgical adjuncts
- Maxillofacial surgery
Background:
- Negative pressure wound therapy (NPWT) has been a key advancement in wound healing for nearly 20 years.
- NPWT accelerates wound closure in acute and chronic wounds.
- Its application in maxillofacial surgery is underutilized due to challenges in achieving an airtight seal on facial contours.
Purpose of the Study:
- To review the basic science of NPWT.
- To explore its potential application in maxillofacial procedures.
- To identify specific maxillofacial surgeries that could benefit from NPWT.
Main Methods:
- Literature review of NPWT basic science.
- Analysis of challenges in applying NPWT to maxillofacial regions.
- Identification of potential benefits for specific maxillofacial procedures.
Main Results:
- NPWT is a proven technique for wound healing.
- Achieving an airtight seal in maxillofacial areas presents unique challenges.
- Potential exists for NPWT to enhance wound closure in maxillofacial applications.
Conclusions:
- Further research and adaptation of NPWT systems are needed for maxillofacial use.
- Successful adaptation could significantly improve outcomes in maxillofacial wound healing.
- NPWT holds promise for advancing care in complex head and neck wound management.
Related Concept Videos
01:30Applications of Integration to Find Hydrostatic Pressure
103
Hydrostatic force is a fluid's total force at rest on a surface. For a horizontal surface submerged at a fixed depth, the pressure is constant and calculated as the product of fluid density, gravitational acceleration, and depth. In the case of a vertical dam wall submerged in water, this force is not evenly distributed due to the increasing pressure with depth. This variation arises from the cumulative weight of the water above each point. Integration is used to account for the continuous...
103
01:23Negative Regulator Molecules
38.6K
Positive regulators allow a cell to advance through cell cycle checkpoints. Negative regulators have an equally important role as they terminate a cell’s progression through the cell cycle—or pause it—until the cell meets specific criteria.
38.6K
00:58Positive, Negative, and Zero Work
22.3K
Work is done on an object when energy is transferred to the object. In other words, work is done when a force acts on a body that undergoes a displacement from one position to another. By definition, the work done by a force is the integral of the force with respect to the displacement along its path. Forces can vary as a function of position, and displacements can occur along various paths between two points. The magnitude of a force multiplied by the cosine of the angle that the force makes...
22.3K
03:02Constant Pressure Calorimetry
97.9K
Calorimetry is a technique used to measure the amount of heat involved in a chemical or physical process or to measure the heat transferred to or from a substance. The heat is exchanged with a calibrated and insulated device called the calorimeter. Calorimetry experiments are based on the assumption that there is no heat exchange between the insulated calorimeter and the external environment. The well-insulated calorimeters prevent the transfer of heat between the calorimeter and its external...
97.9K
00:59Gene Therapy
27.7K
Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
27.7K
02:34Vapor Pressure
41.1K
When a liquid vaporizes in a closed container, gas molecules cannot escape. As these gas phase molecules move randomly about, they will occasionally collide with the surface of the condensed phase, and in some cases, these collisions will result in the molecules re-entering the condensed phase. The change from the gas phase to the liquid is called condensation. When the rate of condensation becomes equal to the rate of vaporization, neither the amount of the liquid nor the amount of the vapor...
41.1K