Related Experiment Video
Updated: Feb 13, 2026

Intravenous and Intra-amniotic In Utero Transplantation in the Murine Model
Published on: October 9, 2018
Recurrent pterygium treatment using mitomycin C, double amniotic membrane transplantation, and a large conjunctival
Yu Monden1, Fumi Hotokezaka1, Ryoji Yamakawa1
1Department of Ophthalmology, Kurume University School of Medicine, Fukuoka, Japan.
Purpose:
The aim of this study was to evaluate the clinical outcomes of surgery for recurrent pterygia using mitomycin C (MMC), double amniotic membrane transplantation (AMT), and a large conjunctival flap.
Patients And Methods:
This retrospective case series included 31 eyes in 31 patients with recurrent pterygia. All patients underwent pterygium excision, application of MMC, double AMT, and placement of a large conjunctival flap. Outcome measures were visual acuity, astigmatism, and recurrence. Recurrence was defined as the presence of fibrovascular proliferative tissue crossing the limbus.
Results:
The patients' mean age was 68.2 years. The mean follow-up period was 3.6 years. The mean preoperative and postoperative best-corrected visual acuities (logMAR conversion) were 0.23 and 0.13, respectively. There was a significant difference between the mean preoperative (-3.85 D) and postoperative (-2.22 D) astigmatism. The recurrence rate was 3.2% (1/31 cases).
Conclusion:
Surgical pterygium excision with application of MMC, double AMT, and placement of a large conjunctival flap was an effective treatment for recurrent pterygia.
Related Concept Videos
Fixing Double-strand Breaks
Fixing Double-strand Breaks
Double Resonance Techniques: Overview
Spin decoupling is usually achieved by...
Introduction to Membrane Proteins
The Resting Membrane Potential
What are Membranes?

