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Chinese research into severe ulcerative colitis has increased in quantity and complexity.

Cheng-Xin Luo1, Zhong-Hui Wen1, Yu Zhen1

  • 1Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.

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|March 23, 2018
PubMed
Summary

Research on severe ulcerative colitis (SUC) in China has grown significantly, with a focus on management strategies. However, studies on salvage therapy for SUC remain limited.

Keywords:
Bibliometric analysisClinical trialsComplexitySalvage therapySevere ulcerative colitisTemporal trendsTraditional Chinese Medicine

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Area of Science:

  • Gastroenterology and Hepatology
  • Bibliometrics
  • Medical Research Trends

Background:

  • Severe ulcerative colitis (SUC) presents significant clinical challenges.
  • Understanding research output is crucial for identifying knowledge gaps and future directions.

Purpose of the Study:

  • To conduct a bibliometric analysis of research output on SUC in China from 2001 to 2015.
  • To assess trends in publication volume, research complexity, and clinical characteristics of SUC.

Main Methods:

  • Bibliometric analysis of publications from Chinese databases (WANFANG, VIP, CNKI) between 2001-2015.
  • Analysis of publication trends, research types, and patient data from SUC-related papers.

Main Results:

  • A total of 201 SUC publications were identified, with a rapid increase in output, particularly in the last 5 years.
  • Research predominantly focused on SUC management, including pharmacotherapy, nutrition, and surgery, with a significant portion on Traditional Chinese Medicine.
  • Data from 6222 SUC patients revealed a male-to-female ratio of 1.38, a colectomy rate of 7.7%, and a short-term mortality rate of 0.8%.

Conclusions:

  • Chinese research on SUC has significantly increased in volume and complexity over 15 years.
  • While management research is prevalent, there is a notable lack of studies focusing on salvage therapy for SUC.