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Draft Genome Sequence of Multidrug-Resistant Stenotrophomonas pavanii BWK1, Isolated from Mareca penelope Feces

Takehiko Kenzaka1, Katsuji Tani2

  • 1Environmental Science and Microbiology, Faculty of Pharmacy, Osaka Ohtani University, Tondabayashi, Japan kenzat@osaka-ohtani.ac.jp.

Genome Announcements
|March 24, 2018
PubMed

Insights

Migratory birds can spread antibiotic resistance. Researchers found a multidrug-resistant bacterium, Stenotrophomonas pavanii BWK1, in duck feces, highlighting avian transmission risks.

Area of Science:

  • Microbiology
  • Environmental Science
  • Genomics

Background:

  • Migratory birds are recognized vectors for disseminating antibiotic-resistant bacteria globally.
  • The increasing prevalence of antimicrobial resistance poses a significant threat to public health.

Purpose of the Study:

  • To isolate and characterize multidrug-resistant bacteria from migratory birds.
  • To investigate the genetic basis of antibiotic resistance in an isolated bacterial strain.

Main Methods:

  • Isolation of bacteria from fecal samples of migratory birds (Mareca penelope).
  • Whole-genome sequencing and analysis of the isolated bacterial strain.
  • Identification of genes conferring antibiotic resistance and virulence factors.

Main Results:

  • A multidrug-resistant Stenotrophomonas pavanii strain, designated BWK1, was successfully isolated from Mareca penelope feces.
  • Genomic analysis revealed the presence of a class A beta-lactamase, a metallo-beta-lactamase, and multiple multidrug efflux pumps in strain BWK1.
  • These genetic determinants confer resistance to a wide range of antibiotics.

Conclusions:

  • Migratory birds, such as Mareca penelope, can act as reservoirs and disseminators of multidrug-resistant bacteria.
  • The genetic makeup of Stenotrophomonas pavanii BWK1 demonstrates a significant potential for contributing to the spread of antibiotic resistance.
  • Understanding avian-mediated transmission is crucial for developing strategies to control antimicrobial resistance.

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