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Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors
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Photosensitive disorders in HIV.

Karen Koch1

  • 1Wits University Donald Gordon Medical Centre, Johannesburg, South Africa.

Southern African Journal of HIV Medicine
|March 24, 2018
PubMed
Summary
This summary is machine-generated.

Photosensitive disorders are common in HIV patients, with HIV itself and certain conditions like pellagra increasing risk. Recognizing and managing these photosensitive conditions, including unique South African disorders, is crucial.

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Area of Science:

  • Dermatology
  • Infectious Diseases
  • Public Health

Background:

  • Photosensitive disorders affect up to 5% of individuals with human immunodeficiency virus (HIV).
  • HIV infection can independently cause photosensitivity.
  • Certain conditions, including photoaggravated drug reactions, porphyria cutanea tarda, and nutritional deficiencies like pellagra, are more prevalent in HIV-positive individuals.

Purpose of the Study:

  • To highlight the increased prevalence and unique manifestations of photosensitive disorders in HIV-positive patients.
  • To emphasize the importance of recognizing these conditions for appropriate patient management.

Main Methods:

  • Review of existing literature on photosensitivity in HIV.
  • Clinical observation and case studies of photosensitive disorders in HIV-positive populations, particularly in South Africa.

Main Results:

  • HIV itself is an independent cause of photosensitivity.
  • Conditions such as porphyria cutanea tarda, pellagra, and drug reactions are more common in HIV patients.
  • Actinic lichenoid leukomelanoderma of HIV, a distinct photosensitive disorder, is associated with advanced HIV in South Africa.

Conclusions:

  • Prompt recognition of photosensitive disorders in HIV patients is essential.
  • Discontinuation of photosensitizing medications should be considered whenever feasible to manage these conditions effectively.