Related Experiment Video
Updated: Feb 12, 2026

Correlative Optical Spectroscopy and Mass Spectrometry Imaging Methodology to Visualise Drug Distribution in a Soft Tissue Section
Published on: June 20, 2025
Facial soft tissue thickness (FSTT) estimation models-And the strength of correlations between craniometric
Carl N Stephan1, Emma Sievwright1
1Laboratory for Human Craniofacial and Skeletal Identification (HuCS-ID Lab), School of Biomedical Sciences, The University of Queensland, Brisbane 4072, Australia.
Abstract:
It has been speculated that craniometric dimensions can be used to improve estimations of facial soft tissue thickness (FSTT) in craniofacial identification. Subsequently, linear regression (LR) models have been published, but the practical utility of these models (lower errors than means) has never been tested/demonstrated. Using 71 living subjects measured by B-mode ultrasound, this study calculates and compares standard errors for previously published LR models and untrimmed FSTT means. Correlations between craniometric dimensions and FSTTs were calculated and regression model reproducibility examined by: generating new models using a 61 subject training set; and three-fold cross validation. Published regression models, applied to the above mentioned new individuals of this study, provided substantially worse estimates of ground truth FSTTs than untrimmed arithmetic means (mean Sest=4.0mm compared to 2.8mm, n=61-71). Correlations between craniometrics and FSTTs were generally small (mean of absolute values=0.17, raw interval=-0.24 to 0.48) and only two of 15 previously published LR models were reproducible (mr-mr' and g-g')-i.e., contained the same independent variable with no more than one other different independent variable entering the model. Under three-fold cross-validation (training sets of 40-41 individuals), no LR equation was reproduced across all three validation test runs. Basic craniometric dimensions do not appear to generally improve FSTT estimations and relationships between craniometric dimensions and FSTTs are much weaker and less reliable than previously thought. B-mode ultrasound data for adult Australians were pooled herein to provide larger sampled and updated FSTT statistics for this cohort (n=118-123).
More Related Videos
Related Concept Videos
Correlations
Correlation and Causation
Correlation versus Causation
If the dependent variable increases or decreases when the independent variable increases, there is a positive or negative...
Acid Strength and Molecular Structure
In the absence of any leveling effect, the acid strength of binary compounds of hydrogen with nonmetals (A) increases as the H-A bond strength decreases down a group in the periodic table. For group 17, the order of increasing acidity is HF < HCl < HBr < HI. Likewise, for group 16, the order of increasing acid strength is H2O < H2S < H2Se < H2Te. Across a row in the periodic table, the acid strength of binary hydrogen compounds increases with increasing...
Correlation
Two variables, for example, a and b, are said to be positively correlated if both variables move in the same direction. In other words, a positive correlation exists between two variables, a and b, if:
Support Reactions in Three Dimensions
Ball and Socket Joint is one of the supports allowing free rotation about any axis. This freedom of rotation is...
Relative Velocity in One Dimension

