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Related Concept Videos

Parallel Processing01:20

Parallel Processing

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The brain processes sensory information rapidly due to parallel processing, which involves sending data across multiple neural pathways at the same time. This method allows the brain to manage various sensory qualities, such as shapes, colors, movements, and locations, all concurrently. For instance, when observing a forest landscape, the brain simultaneously processes the movement of leaves, the shapes of trees, the depth between them, and the various shades of green. This enables a quick and...
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Parallel Resonance01:23

Parallel Resonance

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The parallel RLC circuit is an arrangement where the resistor (R), inductor (L), and capacitor (C) are all connected to the same nodes and, as a result, share the same voltage across them. The parallel RLC circuit is analyzed in terms of admittance (Y), which reflects the ease with which current can flow. The admittance is given by:
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Resistors In Parallel01:23

Resistors In Parallel

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Resistors are in parallel when one end of all the resistors are connected to a continuous wire of negligible resistance and the other end of all the resistors are also connected to one another through a continuous wire of negligible resistance. In the case of a parallel configuration, the potential drop across each resistor is the same. Current through each resistor can be found using Ohm’s law, I = V/R, where the voltage is constant across each resistor. The sum of the individual currents...
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Series and Parallel Capacitors01:14

Series and Parallel Capacitors

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Capacitors, fundamental components in electronic circuits, can be connected in series and/or parallel configurations. Each configuration has different impacts on the overall behavior of the circuit.
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Parallel-axis Theorem01:06

Parallel-axis Theorem

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The parallel-axis theorem provides a convenient and quick method of finding the moment of inertia of an object about an axis parallel to the axis passing through its center of mass. Consider a thin rod as an example. There is a striking similarity between the process of finding the moment of inertia of a thin rod about an axis through its middle, where the center of mass lies, and about an axis through its end using the conventional method. In the conventional method, the concept of linear mass...
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Capacitors in Series and Parallel01:19

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Multiple capacitors connected serve as electrical components in various applications. These multiple capacitors behave as a single equivalent capacitor, and its total capacitance depends on the capacitance of individual capacitors and the type of connections. Capacitors can be arranged in two - orientations, either in series or parallel connections.
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Fabrication and Use of Dry Macroporous Alginate Scaffolds for Viral Transduction of T Cells
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Parallel fabrication of macroporous scaffolds.

Andrew Dobos1, Taraka Sai Pavan Grandhi1, Sudhakar Godeshala2

  • 1Biomedical Engineering, Arizona State University, Tempe, Arizona.

Biotechnology and Bioengineering
|March 26, 2018
PubMed
Summary
This summary is machine-generated.

A new device enables parallel fabrication of 3D polymeric scaffolds, increasing throughput and simplifying retrieval. This versatile method produces macroporous and non-macroporous materials for diverse biotechnological applications.

Keywords:
biomaterialsplasmid DNApolymeric scaffolds

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Area of Science:

  • Biomaterials Engineering
  • Polymer Science
  • Tissue Engineering

Background:

  • 3D polymeric scaffolds are crucial for biocompatibility and tunable properties in various applications.
  • Existing scaffold fabrication methods lack parallelization, low throughput, and easy retrieval of fragile structures.
  • Current molds are often single-use and do not support parallel fabrication of hydrogels and scaffolds.

Purpose of the Study:

  • To introduce a simple device for parallel fabrication of macroporous scaffolds.
  • To enhance throughput and simplify the retrieval of 3D scaffolds.
  • To demonstrate the versatility of the approach for diverse materials and applications.

Main Methods:

  • Developed a novel device for parallel scaffold fabrication.
  • Generated macroporous and non-macroporous materials in parallel.
  • Utilized diverse materials including Amikagel, PLGA, and collagen.

Main Results:

  • Achieved higher throughput and easy retrieval of 3D scaffolds.
  • Successfully generated scaffolds with interconnected and non-interconnected pores.
  • Demonstrated scaffold fabrication from various polymers and hydrogels.

Conclusions:

  • The device-based approach offers a simple, high-throughput method for parallel scaffold fabrication.
  • This technology enhances existing fabrication techniques for biomaterials.
  • Generated scaffolds show potential for applications in plasmid DNA binding and cell loading for biotechnology.