[PERCUTANEOUS TREATMENT OF SMALL RENAL TUMORS BY THERMAL ABLATION]

Amitay Lorber1, Nahum S Goldberg2, Ofer N Gofrit1

  • 1The Urology Department, Hadassah Medical Center.

Harefuah
|March 28, 2018
PubMed
Abstract

Insights

Radiofrequency ablation effectively treats small kidney tumors, achieving a 94% cure rate for tumors up to 30 mm. Repeat treatments are successful for recurrences, making it a viable option for elderly patients or those with high surgical risks.

Area of Science:

  • Urology
  • Oncology
  • Minimally Invasive Procedures

Background:

  • Kidney cancer incidence is rising, with a significant increase in small renal tumors.
  • Radiofrequency ablation (RF) offers a minimally invasive treatment option for small renal tumors, reducing surgical and anesthetic risks.
  • Percutaneous RF ablation is guided by imaging modalities such as ultrasound, CT, or MRI.

Purpose of the Study:

  • To review the outcomes of radiofrequency ablation for treating small renal tumors.
  • To assess the efficacy and recurrence rates of RF ablation in a patient cohort.

Main Methods:

  • A total of 75 patients with small renal tumors were treated with RF ablation between 2007 and 2014.
  • The average tumor diameter was 28.4 mm, with tumors categorized as exophytic or central.
  • Follow-up included imaging at 1, 3, 6, 12 months, and annually thereafter, with a median follow-up of 21 months.

Main Results:

  • Tumor recurrence was observed in 11.4% of patients (9/75), with 8 successfully retreated with RF ablation.
  • Recurrences were more common in tumors larger than 30 mm and those adjacent to renal cysts.
  • One patient died from metastatic renal cell carcinoma (RCC), and two others developed metastatic disease.

Conclusions:

  • Radiofrequency ablation can effectively destroy most small renal tumors, achieving a 94% long-term cure rate for tumors up to 30 mm.
  • Repeat RF ablation sessions are effective for tumor regrowth.
  • This treatment is recommended for older patients, those with limited life expectancy, or when surgical risks are prohibitive.

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