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Updated: Feb 12, 2026

Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
[PERCUTANEOUS TREATMENT OF SMALL RENAL TUMORS BY THERMAL ABLATION]
Amitay Lorber1, Nahum S Goldberg2, Ofer N Gofrit1
1The Urology Department, Hadassah Medical Center.
Introduction:
Kidney cancer accounts for approximately 2-3 % of all types of cancers. Renal tumors prevalence and especially the prevalence of small renal tumors, is on the rise. About half of the tumors currently diagnosed are smaller than 4 cm. Minimally invasive methods of radiofrequency ablation technology were recently developed for the treatment of small renal tumors and are characterized by reducing the surgical and anesthetic risk. The ablation is performed with a percutaneous approach guided by ultrasound, CT or MRI. We reviewed the results of this treatment.
Methods:
A total of 75 patients with a mean age of 69.5 years (27 - 90) were treated using RF during the period 2007-2014. The average tumor diameter was 28.4 mm (11-58 mm); 40 tumors were exophytic and 30 were central. Monitoring protocol after treatment included imaging after 1, 3, 6, 12 months subsequent to treatment and later annually; median follow-up time was 21 months (1 - 97).
Results:
Evidence of tumor recurrence was observed in 9 patients (11.4%); 8 were treated successfully by another RF session. Cases in which recurrence was observed were characterized by a tumor larger than 30 mm (5/9) and adjacent to renal cysts (3/9); 5 of the lesions were central (endophytic) (P=0.5). One patient died due to metastatic RCC and a metastatic disease developed in two additional patients who died of other causes.
Conclusions:
It is possible to destroy most of the small renal tumors by RF ablation. When the tumor size is up to 30 mm, a 94% long-term cure may be reached. In the event of renewed growth of the tumor, the treatment can be repeated with good results. In light of short-term experience, it is recommended to limit this treatment to older patients, with a short life expectancy or when anesthetic risks prohibit surgery.
Insights
Radiofrequency ablation effectively treats small kidney tumors, achieving a 94% cure rate for tumors up to 30 mm. Repeat treatments are successful for recurrences, making it a viable option for elderly patients or those with high surgical risks.
Area of Science:
- Urology
- Oncology
- Minimally Invasive Procedures
Background:
- Kidney cancer incidence is rising, with a significant increase in small renal tumors.
- Radiofrequency ablation (RF) offers a minimally invasive treatment option for small renal tumors, reducing surgical and anesthetic risks.
- Percutaneous RF ablation is guided by imaging modalities such as ultrasound, CT, or MRI.
Purpose of the Study:
- To review the outcomes of radiofrequency ablation for treating small renal tumors.
- To assess the efficacy and recurrence rates of RF ablation in a patient cohort.
Main Methods:
- A total of 75 patients with small renal tumors were treated with RF ablation between 2007 and 2014.
- The average tumor diameter was 28.4 mm, with tumors categorized as exophytic or central.
- Follow-up included imaging at 1, 3, 6, 12 months, and annually thereafter, with a median follow-up of 21 months.
Main Results:
- Tumor recurrence was observed in 11.4% of patients (9/75), with 8 successfully retreated with RF ablation.
- Recurrences were more common in tumors larger than 30 mm and those adjacent to renal cysts.
- One patient died from metastatic renal cell carcinoma (RCC), and two others developed metastatic disease.
Conclusions:
- Radiofrequency ablation can effectively destroy most small renal tumors, achieving a 94% long-term cure rate for tumors up to 30 mm.
- Repeat RF ablation sessions are effective for tumor regrowth.
- This treatment is recommended for older patients, those with limited life expectancy, or when surgical risks are prohibitive.
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