[Long-Term Results after Trabeculectomy Combined with Mitomycin C and Ologen Implant]
Sofia Fili1, Sabine Seddig1, Markus Kohlhaas1
1Klinik für Augenheilkunde, St.-Johannes-Hospital.
Background:
The Ologen implant consists of a biodegradable collagen and glycosaminoglycan and is intended to avoid postoperative bleb scarring or encapsulation.
Materials And Methods:
In a retrospective clinical study, 806 patients with advanced glaucoma were treated with trabeculectomy combined with mitomycin C0.02% and Ologen implant. The follow-up time of the study was 8 years.
Results:
A long-term reduction of the intraocular pressure below 16 mmHg was achieved in 92.6% of the patients without glaucoma eye drops in the long-term observation period. The rate of complication was very low during the postoperative period and additional surgical procedures for over-filtration with subsequent choroidal detachment were seen in 6.8% of the patients. A failure of the combined operation with phacoemulsification and implantation of an intraocular lens resulted in revision of the bleb or the application of compressive sutures in 3.35% of patients within 8 years.
Conclusion:
The Ologen implant was introduced in glaucoma surgery to increase the effectiveness of trabeculectomy and to reduce the complications. Trabeculectomy combined with mitomycin C0.02% and an Ologen implant provides a satisfactory filtering effect without the undesirable effects of postoperative fibrosis.
More Related Videos
08:30Subdural Soft Electrocorticography ECoG Array Implantation and Long-Term Cortical Recording in Minipigs
Published on: March 31, 2023
10:52Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation
Published on: October 2, 2015
Related Concept Videos
Long-term Depression
Long-term Depression
Calcium Ion Concentration Mechanism
If over...
Long-term Potentiation
Long-term Potentiation
Hebbian LTP
LTP can occur when...
Directional Terms
Long-Term Memory
Long-term memory can be categorized into two primary types: explicit and implicit memory. Explicit memory, also known as declarative memory, involves the conscious recollection of information that we deliberately try to remember, recall, and articulate. This type of memory encompasses specific facts, events, and...
