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Implementation of Venous Thromboembolism Prophylaxis Guidelines in Clinical Practice: A Retrospective Study in Two

Srećko Marušić1,2, Aleksandar Knežević3, Vesna Bačić Vrca4

  • 1Department of Clinical Pharmacology, Dubrava University Hospital, Zagreb, Croatia.

Acta Clinica Croatica
|March 30, 2018
PubMed

Insights

Implementation of venous thromboembolism prevention guidelines in Croatian hospitals was insufficient. Few high-risk patients received thromboprophylaxis, with no significant change after guideline introduction.

Area of Science:

  • Medical Practice
  • Clinical Guidelines
  • Thromboprophylaxis

Background:

  • Venous thromboembolism (VTE) is a significant clinical concern.
  • Evidence-based guidelines aim to improve VTE prevention.
  • The 9th edition of American College of Chest Physicians (ACCP9) guidelines provide recommendations for VTE prophylaxis.

Purpose of the Study:

  • To evaluate the clinical implementation of ACCP9 guidelines for VTE prevention in nonsurgical patients.
  • To assess thromboprophylaxis rates before and after guideline implementation in two Croatian hospitals.

Main Methods:

  • Retrospective analysis of medical charts for 850 nonsurgical patients across two hospitals.
  • Data collected from periods before and after ACCP9 guideline dissemination.
  • Comparison of thromboprophylaxis rates between hospitals and time periods.

Main Results:

  • No statistically significant difference in thromboprophylaxis rates for high-risk patients post-guideline implementation.
  • Dubrava University Hospital consistently had higher thromboprophylaxis rates than Zadar General Hospital.
  • Overall implementation of evidence-based thromboprophylaxis guidelines was found to be insufficient.

Conclusions:

  • The ACCP9 guidelines for VTE prevention were inadequately implemented in the studied Croatian hospitals.
  • Further strategies are needed to improve adherence to evidence-based thromboprophylaxis protocols.
  • Hospital-specific factors may influence guideline adoption and patient care outcomes.

Keywords:
CroatiaPharmacy and therapeutics committeePractice guidelines as topicRetrospective studiesVenous thromboembolism

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