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Updated: Feb 12, 2026

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Published on: August 22, 2012

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Tonsillar Lymphoma in Children According to Age Group: A Systematic Review

Guilherme-Machado de Carvalho1, Henrique-Furlan Pauna1, Agrício-Nubiato Crespo1

  • 1Department of Otorhinolaryngology, Head and Neck Surgery, University of Campinas, Campinas, São Paulo, Brazil.

Iranian Journal of Otorhinolaryngology
|March 30, 2018
PubMed

Insights

Pediatric tonsillar lymphoma presents differently by age. While tonsillar asymmetry is common in all children, specific symptoms like snoring, lymphadenopathy, and dysphagia vary with age, aiding early diagnosis.

Area of Science:

  • Pediatric Oncology
  • Head and Neck Malignancies
  • Clinical Manifestations

Background:

  • Lymphoma is a frequent pediatric head and neck cancer.
  • Early diagnosis of tonsillar lymphoma is crucial for improved prognosis.
  • Understanding age-specific clinical signs aids timely intervention.

Purpose of the Study:

  • To analyze clinical manifestations of pediatric tonsillar lymphoma.
  • To stratify symptoms based on different pediatric age groups.
  • To identify key diagnostic indicators for early detection.

Main Methods:

  • Systematic literature review (1996-2012) across multiple databases.
  • Inclusion of pediatric case reports (patients ≤18 years).
  • Focus on clinical features at diagnosis.

Main Results:

  • 53 pediatric cases identified from 13 articles.
  • Tonsillar asymmetry is the most prevalent sign across all ages.
  • Age-specific signs include snoring (<5 years), lymphadenopathy (6-10 years), and dysphagia (11-18 years).
  • Burkitt's lymphoma is the most common type, followed by B-cell lymphoma.

Conclusions:

  • Clinical presentation of pediatric tonsillar lymphoma is age-dependent.
  • Tonsillar asymmetry serves as a consistent indicator regardless of age.
  • Recognizing age-specific symptoms improves diagnostic accuracy.
Abstract

Keywords:
ChildrenLymphadenopathyLymphomaTonsillar asymmetryTonsillar neoplasm

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