Related Experiment Video
Updated: Feb 12, 2026

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines
Published on: April 21, 2022
SYSTEMS-2: A randomised phase II study of radiotherapy dose escalation for pain control in malignant pleural
M Ashton1,2, N O'Rourke2, N Macleod2
1Institute of Cancer Sciences, University of Glasgow, UK.
Abstract:
SYSTEMS-2 is a randomised study of radiotherapy dose escalation for pain control in 112 patients with malignant pleural mesothelioma (MPM). Standard palliative (20 Gy/5#) or dose escalated treatment (36 Gy/6#) will be delivered using advanced radiotherapy techniques and pain responses will be compared at week 5. Data will guide optimal palliative radiotherapy in MPM.
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