Related Experiment Video
Updated: Feb 12, 2026

Phage-Mediated Genetic Manipulation of the Lyme Disease Spirochete Borrelia burgdorferi
Published on: September 28, 2022
Lyme Carditis and High-Degree Atrioventricular Block
Douglas Wan1, Crystal Blakely1, Pamela Branscombe1
1Department of Medicine, Division of Cardiology, Queen's University, Kingston, Ontario, Canada.
Lyme disease is rising in Canada, with cardiac complications like heart block becoming more common. Early diagnosis of Lyme carditis is crucial to prevent severe heart issues and the need for pacemakers.
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Background:
- Lyme disease incidence has increased sixfold in Canada since 2009.
- Lyme carditis, particularly high-degree atrioventricular block, is an emerging concern.
- Diagnosis can be challenging due to varied, nonspecific presentations.
Purpose of the Study:
- To present the first Canadian series of Lyme carditis cases.
- To highlight the clinical manifestations of Lyme carditis.
- To emphasize the importance of early diagnosis and management.
Main Methods:
- Retrospective case series.
- Analysis of 5 cases of Lyme carditis over a 2-year period.
- Review of clinical presentations and outcomes.
Main Results:
- Five cases of high-degree atrioventricular block due to Lyme carditis were identified.
- Presentations varied, requiring a high index of suspicion.
- Prompt recognition and management were associated with avoiding permanent pacemaker implantation.
Conclusions:
- Lyme carditis is an important cause of conduction disorders in Canada.
- Early suspicion and diagnosis are critical for effective management.
- Timely intervention may prevent the need for permanent pacemakers.
More Related Videos
05:16Whole-Mount Immunofluorescence Staining, Confocal Imaging and 3D Reconstruction of the Sinoatrial and Atrioventricular Node in the Mouse
Published on: December 22, 2020
08:23Feeding of Ticks on Animals for Transmission and Xenodiagnosis in Lyme Disease Research
Published on: August 31, 2013
Related Concept Videos
One-Degree-of-Freedom System
A one-degree-of-freedom system is defined by an independent variable that determines its state and behavior. One example of a one-degree-of-freedom system is a simple harmonic oscillator, such as a...
Degrees of Freedom
For example, suppose there are three unknown numbers whose mean is 10; although we can freely assign values to the first and second numbers, the value of the last number can not be arbitrarily assigned.
Degrees of Freedom
For example, suppose there are three unknown numbers whose mean is 10; although we can freely assign values to the first and second numbers, the value of the last number can not be arbitrarily...
Degree of Unsaturation
The degree of unsaturation for hydrocarbons is U = (2C + 2 − H) / 2, where C is the number of carbon atoms and H is the number of hydrogen atoms.
Radian and Degree Measure
Degree of Curvature and Radius of Curvature