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[Current problems of lactase deficiency].

L N Valenkevich

    Voprosy Pitaniia
    |July 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Lactose malabsorption affects 14.4% of healthy adults, increasing with age. Gastrointestinal diseases significantly raise the risk of secondary lactose malabsorption, impacting treatment strategies.

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    Area of Science:

    • Gastroenterology
    • Human Physiology
    • Nutritional Science

    Context:

    • Lactose malabsorption prevalence varies across populations and age groups.
    • Gastrointestinal diseases are potential causes of secondary lactose malabsorption.
    • Disaccharidase activity is crucial for lactose digestion.

    Purpose:

    • To determine the prevalence of lactose malabsorption in healthy individuals and patients with gastrointestinal diseases.
    • To investigate the relationship between age, ethnicity, and lactose malabsorption.
    • To assess the incidence of secondary lactose malabsorption in various gastrointestinal conditions.

    Summary:

    • A study involving 500 healthy subjects and 262 gastrointestinal patients assessed lactose malabsorption via lactose loading and blood sugar tests.

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  • Lactose malabsorption was found in 14.4% of healthy individuals, with higher rates in older adults (20% aged 60-89).
  • Secondary lactose malabsorption was prevalent in patients with ulcerative colitis (44%), chronic enterocolitis (33%), and chronic gastritis (23.5% with low secretory function).

    • Impact:

    • Findings highlight the significant prevalence of lactose malabsorption, particularly in aging populations and those with specific gastrointestinal disorders.
    • Results underscore the importance of considering lactose malabsorption in the differential diagnosis of gastrointestinal symptoms.
    • This research can inform clinical practice regarding dietary recommendations and management strategies for patients with lactose intolerance and gastrointestinal diseases.