Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Molecular Models02:00

Molecular Models

43.9K
Physical models representing molecular architectures of chemical compounds play essential roles in understanding chemistry. The use of molecular models makes it easier to visualize the structures and shapes of atoms and molecules.
43.9K
The Bohr Model02:18

The Bohr Model

81.1K
Following the work of Ernest Rutherford and his colleagues in the early twentieth century, the picture of atoms consisting of tiny dense nuclei surrounded by lighter and even tinier electrons continually moving about the nucleus was well established. This picture was called the planetary model since it pictured the atom as a miniature “solar system” with the electrons orbiting the nucleus like planets orbiting the sun. The simplest atom is hydrogen, consisting of a single proton as the...
81.1K
Stereotype Content Model02:16

Stereotype Content Model

15.5K
The Stereotype Content Model (SCM) was first proposed by Susan Fiske and her colleagues (Fiske, Cuddy, Glick & Xu, 2002; see also Fiske, 2012 and Fiske, 2017). The SCM specifies that when someone encounters a new group, they will stereotype them based on two metrics: warmth—or that group’s perceived intent, and how likely they are to provide help or inflict harm—and competence—or their ability to carry out that objective. Depending on the warmth-competence...
15.5K
Pharmacodynamic Models: Direct Effect Model and Indirect Response Model01:29

Pharmacodynamic Models: Direct Effect Model and Indirect Response Model

1
Pharmacodynamic models are essential tools in understanding the relationship between drug concentrations and their effects on biological systems. By characterizing the dynamics of drug action, these models guide dose selection, optimize therapeutic efficacy, and inform the development of new drugs. Two major classes of pharmacodynamic models include direct effect and indirect response models.Direct Effect ModelsDirect effect models describe the immediate relationship between drug concentration...
1
Compartment Models: Two-Compartment Model01:20

Compartment Models: Two-Compartment Model

7.2K
The two-compartment model divides the body into central and peripheral compartments to account for varying blood perfusion rates among organs and tissues, affecting drug distribution. The central compartment includes blood and highly perfused tissues with rapid drug distribution, while the peripheral compartment contains tissues with slower drug distribution. After a single IV bolus dose, the drug concentration is high in plasma and low in tissues. The drug distribution between compartments...
7.2K
Clearance Models: Physiological Models01:09

Clearance Models: Physiological Models

329
Drug clearance is a critical pharmacokinetic process involving the irreversible removal of drugs from the body through various organs over a specified time period. Physiological models are indispensable in determining organ-specific clearance, defined by the proportion of the drug eliminated per unit of time from the organ's blood volume.
The organ's clearance rate depends on the blood flow to the organ and the extraction ratio (E). The extraction ratio describes the organ's...
329

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Infection thresholds for two interacting pathogens in a wild animal population.

Mathematical biosciences·2024
Same author

How immune dynamics shape multi-season epidemics: a continuous-discrete model in one dimensional antigenic space.

Journal of mathematical biology·2024
Same author

Infection dynamics in ecosystems: on the interaction between red and grey squirrels, pox virus, pine martens and trees.

Journal of the Royal Society, Interface·2021
Same author

Combining mutation and horizontal gene transfer in a within-host model of antibiotic resistance.

Mathematical biosciences·2021
Same author

Characterizing reservoirs of infection and the maintenance of pathogens in ecosystems.

Journal of the Royal Society, Interface·2020
Same author

A simple influenza model with complicated dynamics.

Journal of mathematical biology·2018

Related Experiment Video

Updated: Feb 12, 2026

Laser-assisted Cytoplasmic Microinjection in Livestock Zygotes
08:59

Laser-assisted Cytoplasmic Microinjection in Livestock Zygotes

Published on: October 5, 2016

9.6K

Modelling leptospirosis in livestock.

A M Babylon1, M G Roberts1, G C Wake1

  • 1Institute of Natural and Mathematical Sciences, Massey University, Private Bag 102 904, North Shore Mail Centre 1311, Auckland 0745, New Zealand.

Theoretical Population Biology
|March 31, 2018
PubMed
Summary
This summary is machine-generated.

New Zealand faces high rates of leptospirosis, an occupational disease spread from livestock. This study models infection dynamics in farmed animals to predict disease persistence and inform control strategies.

Keywords:
Compartmental modelCyclicalLeptospirosisLivestockMathematical modelPeriodic

More Related Videos

Biocontained Carcass Composting for Control of Infectious Disease Outbreak in Livestock
14:34

Biocontained Carcass Composting for Control of Infectious Disease Outbreak in Livestock

Published on: May 6, 2010

11.3K
Lab-Scale Model to Evaluate Odor and Gas Concentrations Emitted by Deep Bedded Pack Manure
06:52

Lab-Scale Model to Evaluate Odor and Gas Concentrations Emitted by Deep Bedded Pack Manure

Published on: July 19, 2018

6.9K

Related Experiment Videos

Last Updated: Feb 12, 2026

Laser-assisted Cytoplasmic Microinjection in Livestock Zygotes
08:59

Laser-assisted Cytoplasmic Microinjection in Livestock Zygotes

Published on: October 5, 2016

9.6K
Biocontained Carcass Composting for Control of Infectious Disease Outbreak in Livestock
14:34

Biocontained Carcass Composting for Control of Infectious Disease Outbreak in Livestock

Published on: May 6, 2010

11.3K
Lab-Scale Model to Evaluate Odor and Gas Concentrations Emitted by Deep Bedded Pack Manure
06:52

Lab-Scale Model to Evaluate Odor and Gas Concentrations Emitted by Deep Bedded Pack Manure

Published on: July 19, 2018

6.9K

Area of Science:

  • Veterinary epidemiology
  • Mathematical modeling
  • Infectious disease dynamics

Background:

  • New Zealand has one of the world's highest per capita rates of human leptospirosis.
  • Leptospirosis is the most common occupational disease in New Zealand, primarily transmitted from livestock (deer, sheep, cattle).

Purpose of the Study:

  • To develop and analyze a cyclical mathematical model for leptospirosis infection dynamics in New Zealand farmed livestock.
  • To predict conditions influencing the persistence of leptospirosis within livestock populations.

Main Methods:

  • A cyclical model was developed to simulate leptospirosis transmission dynamics.
  • Analysis included determining the limit cycle, bifurcation diagram, and quasi-R 0 value.
  • Leptospire death rate was utilized as a control parameter in the model.

Main Results:

  • The study determined key epidemiological parameters and analyzed the model's behavior under varying conditions.
  • Case studies using previously published parameter values generated figures to demonstrate analytical results.
  • The model successfully predicted conditions under which leptospirosis infection persists in livestock populations.

Conclusions:

  • Mathematical modeling provides a valuable tool for understanding and predicting infectious disease dynamics in livestock.
  • The developed model can inform strategies for controlling and preventing leptospirosis in New Zealand's agricultural sector.