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Type D personality and coronary atherosclerotic plaque vulnerability: The potential mediating effect of health

Fangman Cheng1, Ping Lin1, Yini Wang2

  • 1College of Nursing of Harbin Medical University, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.

Journal of Psychosomatic Research
|April 1, 2018
PubMed

Insights

Type D personality is linked to vulnerable coronary plaque in patients with coronary artery disease. Health behaviors, specifically psychological stress and living habits, significantly mediate this association, highlighting potential intervention points.

Area of Science:

  • Cardiology
  • Psychology
  • Health Behavior Research

Background:

  • Type D personality, characterized by negative affectivity and social inhibition, has been anecdotally linked to increased cardiovascular risk.
  • Coronary plaque vulnerability is a critical determinant of acute coronary events.

Purpose of the Study:

  • To investigate the mediating role of health behaviors in the relationship between Type D personality and coronary plaque vulnerability.
  • To identify specific health behaviors that influence the association between psychological traits and cardiovascular pathology.

Main Methods:

  • A cohort of 319 coronary artery disease patients were evaluated using self-administered questionnaires for Type D personality and health behaviors.
  • Coronary plaque vulnerability was assessed using optical coherence tomography, analyzing plaque characteristics, accompaniments, and outcomes.

Main Results:

  • Type D personality independently predicted lipid plaque, thin cap fibroatheroma (TCFA), rupture, and lipid arc.
  • Psychological stress significantly mediated the association between Type D personality and lipid plaque, TCFA, and rupture.
  • Living habits also significantly mediated the relationship between Type D personality and lipid plaque and TCFA.

Conclusions:

  • Health behaviors, including psychological stress and living habits, act as significant mediators between Type D personality and coronary plaque vulnerability.
  • These findings suggest that interventions targeting health behaviors may mitigate the adverse cardiovascular effects associated with Type D personality.
Abstract

Keywords:
Health behaviorMediation analysisPlaque vulnerabilityType D personality

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