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Updated: Feb 12, 2026

Generation of Retinal Organoids from Healthy and Retinal Disease-Specific Human-Induced Pluripotent Stem Cells
Published on: December 9, 2022
Retinal Cell Fate Specification
Suqian Wu1, Kun-Che Chang2, Jeffrey L Goldberg3
1Byers Eye Institute, Department of Ophthalmology, School of Medicine, Stanford University, Palo Alto, CA 94303, USA; Eye, Ear, Nose & Throat Hospital, Department of Ophthalmology and Visual Science, Fudan University, Shanghai, 200031, P.R. China; These authors contributed equally.
Abstract:
How are different neural cell types generated from progenitor cells? In 1990, Turner et al. used new lineage tracing techniques to show that different cells in the mammalian retina share their progenitor origin. The findings established a key step toward our understanding of how multipotent progenitor cells give rise to complex circuitry in the retina.
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