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[Post-traumatic pulmonary aspergilloma]
M Isnard1, E Hullo2, Y Robert3
1CS10217, clinique universitaire de pneumologie, CHU de Grenoble-Alpes, 38043 Grenoble cedex 9, France.
Introduction:
Aspergillomas occur due to colonization of a pre-existing pulmonary, bronchial or pleural cavity by Aspergillus spp. Often asymptomatic, this pathology can reveal itself by recurrent haemoptysis or when bacterial superinfections occur. Aspergillomas occurring in post-traumatic cavities are rare and their management is poorly codified.
Case Report:
A child suffered from a chest wound at the age of 13 years. Two years later, investigation of recurrent haemoptysis revealed a residual pneumatocele in the right lower lobe colonized by Aspergillus spp. Initial treatment with systemic azole antifungals was unsuccessful because of digestive and ophthalmological intolerance. Surgical treatment by right lower lobectomy was finally decided on by the multidisciplinary team. This revealed an intrabronchial foreign body of vegetal type with cellulosic reinforcement, causing a polymorphic granulomatous reaction around, and associated with a proliferation of filamentous fungi including Aspergillus fumigatus. Surgery was followed by liposomal amphotericin B treatment for three weeks with a favourable outcome.
Conclusions:
This clinical case illustrates the benefits of surgical management of post-traumatic aspergillomas, even in children, in order to eradicate the aspergillus implant and to remove any foreign body to prevent recurrence.
Insights
Surgical intervention is effective for managing post-traumatic pulmonary aspergillomas in children. Removing the foreign body and aspergillus implant prevents recurrence, even after antifungal treatment failure.
Area of Science:
- Pulmonology
- Mycology
- Pediatric Surgery
Background:
- Aspergillomas are fungal infections in pre-existing lung cavities, often asymptomatic but can cause hemoptysis or secondary infections.
- Post-traumatic pulmonary aspergillomas are rare and their treatment is not well-established.
Observation:
- A 13-year-old patient developed a pulmonary aspergilloma in a post-traumatic cavity.
- Recurrent hemoptysis led to the discovery of Aspergillus species colonization.
- Initial antifungal treatment failed due to intolerance.
Findings:
- Surgical lobectomy revealed an intrabronchial foreign body and Aspergillus fumigatus.
- The foreign body caused granulomatous inflammation.
- Post-operative antifungal treatment with liposomal amphotericin B was successful.
Implications:
- Surgical management is crucial for eradicating post-traumatic pulmonary aspergillomas.
- Foreign body removal is essential to prevent fungal implant recurrence.
- This approach offers a favorable outcome, even in pediatric cases.
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