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Sensitivity analysis of the noise-induced oscillatory multistability in Higgins model of glycolysis
1Institute of Natural Sciences and Mathematics, Ural Federal University, Lenina, 51, 620000 Ekaterinburg, Russia.
Abstract:
A phenomenon of the noise-induced oscillatory multistability in glycolysis is studied. As a basic deterministic skeleton, we consider the two-dimensional Higgins model. The noise-induced generation of mixed-mode stochastic oscillations is studied in various parametric zones. Probabilistic mechanisms of the stochastic excitability of equilibria and noise-induced splitting of randomly forced cycles are analysed by the stochastic sensitivity function technique. A parametric zone of supersensitive Canard-type cycles is localized and studied in detail. It is shown that the generation of mixed-mode stochastic oscillations is accompanied by the noise-induced transitions from order to chaos.
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