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Cochlear implantation in children with auditory neuropathy spectrum disorder: A multicenter study on auditory

Ahmad Daneshi1, Marjan Mirsalehi1, Seyed Basir Hashemi2

  • 1ENT and Head & Neck Research Center and Department, Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences (IUMS), Tehran, Iran.

International Journal of Pediatric Otorhinolaryngology
|April 2, 2018
PubMed

Insights

Cochlear implantation significantly improves auditory performance and speech in children with auditory neuropathy spectrum disorder (ANSD). Early implantation (≤24 months) shows greater long-term benefits for auditory skills and speech intelligibility.

Area of Science:

  • Audiology
  • Pediatric Otolaryngology
  • Neuroscience

Background:

  • Auditory Neuropathy Spectrum Disorder (ANSD) presents unique challenges in auditory rehabilitation.
  • Cochlear implantation is a potential treatment for severe-to-profound hearing loss in children with ANSD.
  • The impact of age at implantation on outcomes in ANSD requires further investigation.

Purpose of the Study:

  • To evaluate auditory performance and speech production in children with ANSD post-cochlear implantation.
  • To assess the influence of age at cochlear implantation on auditory and speech outcomes.

Main Methods:

  • A cohort of 136 children with ANSD underwent cochlear implantation across four centers.
  • Patients were grouped based on age at implantation: ≤24 months (Group I) and >24 months (Group II).
  • Categories of Auditory Performance (CAP) and Speech Intelligibility Rating (SIR) scores were assessed at 1 and 2 years post-implantation.

Main Results:

  • Significant improvements in CAP scores were observed in all patients post-implantation (p<0.001).
  • While Group II showed greater initial CAP improvement, Group I demonstrated significantly higher CAP improvement overall (p<0.001).
  • Group I also showed significantly higher SIR improvement by the second year (p=0.003), with no significant SIR difference at earlier follow-ups.

Conclusions:

  • Cochlear implantation is effective in enhancing auditory performance and speech production in children with ANSD.
  • Age at the time of cochlear implantation significantly influences the degree of auditory and speech improvement.
  • Earlier cochlear implantation (≤24 months) appears to yield superior long-term auditory and speech outcomes in this population.
Abstract

Keywords:
Auditory dys-synchronyAuditory neuropathyAuditory neuropathy spectrum disorderChildrenCochlear implantation

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