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Production of polyclonal antibodies against the cellular IFN-gamma receptor

A Fassio1, F Cofano, G Cavallo

  • 1Istituto di Microbiologia, Università degli Studi di Torino.

Giornale Di Batteriologia, Virologia Ed Immunologia
|January 1, 1986
PubMed

In this work we consider the possibility to produce a polyclonal antibody against murine interferon gamma receptors by immunizing rabbits with the complex receptor-IFN-gamma immunoprecipitated by a monoclonal antibody (AN-18) recognising the ligand bound to the receptor. Using the Western Blotting technique it has been found a polyclonal serum directed against a protein (90 kDa) that could represent the murine IFN-gamma membrane receptor.

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