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Updated: Feb 12, 2026
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Direct Drug Delivery to Kidney via the Renal Artery
Published on: April 17, 2021
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[Evaluation of living kidney donors renal function]
François Gaillard1, Marie Courbebaisse2
1Service de transplantation rénale, hôpital Necker, 145, rue de Sèvres, 75015 Paris, France; Université Paris Descartes, Sorbonne Paris Cité, 145, rue de Sèvres, 75015 Paris, France.
Nephrologie & Therapeutique
|April 3, 2018
Summary
Living kidney donation carries a lower end-stage renal disease risk than the general population. However, donation may increase this risk, necessitating better understanding of long-term consequences and improved donor screening.
Area of Science:
- Nephrology
- Transplantation Medicine
- Public Health
Background:
- Living kidney donation is a vital procedure for end-stage renal disease (ESRD) patients.
- Previous studies indicated a lower ESRD risk in donors compared to the general population.
- Recent research highlights a potential increase in ESRD risk post-donation, underscoring the need for long-term follow-up.
Purpose of the Study:
- To define the long-term consequences of living kidney donation.
- To review the physiology of kidney donation.
- To discuss current international guidelines for living donor screening.
Main Methods:
- Literature review of studies on living kidney donor outcomes.
- Analysis of renal function evaluation in donor screening.
- Synthesis of physiological data related to kidney donation.
Main Results:
- Living kidney donors generally have a lower risk of ESRD than the general population.
- Evidence suggests an elevated ESRD risk following kidney donation.
- Precise understanding of kidney donation physiology is crucial for effective screening.
Conclusions:
- Long-term outcomes for living kidney donors require further definition.
- Optimizing predonation screening necessitates a thorough understanding of kidney donation physiology.
- International guidelines for living donor evaluation should be continuously refined.
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