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Updated: Feb 12, 2026

Phase Diagram Characterization Using Magnetic Beads as Liquid Carriers
Published on: September 4, 2015
Magnetic solid-phase extraction based on magnetic zeolitic imazolate framework-8 coupled with high performance liquid
Juanqiang Wang1, Xuerui Liu1, Yun Wei1
1State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, 15 Beisanhuan East Road, Chaoyang District, Beijing 100029, China.
Abstract:
In this study, magnetic zeolitic imazolate framework-8 (Fe3O4@ZIF-8) was successfully synthesized by a typical hydrothermal method. The facile magnetic solid-phase extraction (MSPE) based on Fe3O4@ZIF-8 was proposed for concentrating polymer additives (antioxidants and ultraviolet absorbers). The conditions of MSPE process were optimized. An analytical method of magnetic solid-phase extraction followed by high performance liquid chromatography (MSPE-HPLC) was successfully established for the simultaneous determination of seven polymer additives in drinks and foods packed with plastic. The established method showed good precision, reproducibility, stability, and accuracy with the low limits of detection (0.03-0.15 ng/mL) and limits of quantification (0.08-0.50 ng/mL). The results of this study indicated the Fe3O4@ZIF-8 coupled with HPLC provided an efficient enrichment and determination method for polymer additives in drinks and foods.
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