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Pagetoid Bowen Disease Initially Misdiagnosed as Ectopic Extramammary Paget's Disease
Jaewon Lee1, Minwoo Kim1, Jungyoon Moon1
1Department of Dermatology, SMG-SNU Boramae Medical Center, Seoul, Korea.
Abstract:
Pagetoid Bowen disease is a histological variant of Bowen disease which demonstrates large pale staining cells (pagetoid cells). It requires differential diagnosis from other cutaneous malignancies with similar patterns, such as extramammary Paget's disease (EMPD) and Pagetoid melanoma in situ. Herein, we report a case of Pagetoid Bowen disease which was initially misdiagnosed as ectopic EMPD.
Insights
Pagetoid Bowen disease, a variant of Bowen disease, presents with distinctive pagetoid cells. Accurate diagnosis is crucial to differentiate it from similar skin cancers like extramammary Paget's disease.
Area of Science:
- Dermatopathology
- Oncology
Background:
- Pagetoid Bowen disease is a rare histological variant of Bowen disease.
- Distinguishing it from other cutaneous malignancies is essential for proper patient management.
Observation:
- The case presented initially mimicked ectopic extramammary Paget's disease (EMPD).
- Pagetoid cells are characteristic features requiring careful histological evaluation.
Findings:
- The study highlights a case of Pagetoid Bowen disease.
- Initial misdiagnosis as ectopic EMPD underscores diagnostic challenges.
Implications:
- Emphasizes the need for thorough differential diagnosis in dermatopathology.
- Accurate identification of Pagetoid Bowen disease is critical for appropriate treatment and prognosis.