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Updated: Feb 12, 2026

Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases
Published on: November 22, 2024
[Prophylaxis and Therapy of Malaria: Current Recommendations]
Christof D Vinnemeier1, Thierry Rolling1
1I. Medizinische Klinik und Poliklinik, Sektionen Infektiologie und Tropenmedizin, Universitätsklinikum Hamburg-Eppendorf;Bernhard-Nocht-Institut für Tropenmedizin, Hamburg.
Abstract:
Malaria incidence is decreasing on a global scale, while the number of imported cases has remained at a high level in Germany. To decrease this number, counselling of travellers to malaria-endemic regions is important. Patients to high risk countries need regular chemoprophylaxis. The alternative of stand-by emergency treatment for travellers to regions with low or medium risk has been met with growing criticism. For the treatment of all malaria cases, artemisinins are a mainstay of treatment. Regular follow-up is warranted to prevent relapses. After treatment with intravenous artesunate for complicated malaria, delayed haemolysis must be kept in mind. A special situation has risen in Germany since 2014 with a growing number of Eritrean migrants presenting with Plasmodium vivax malaria. These patients need an additional course of primaquine to prevent relapses.
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