Related Experiment Video For Chest radiography
Updated: Feb 12, 2026

Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing
Published on: October 10, 2025
Missed Lung Cancer
Rydhwana Hossain1, Carol C Wu2, Patricia M de Groot2
1Thoracic Imaging and Interventions, Massachusetts General Hospital, 55 Fruit Street FND 202, Boston, MA 02114, USA.
Abstract:
The chest radiograph is one of the most commonly used imaging studies and is the modality of choice for initial evaluation of many common clinical scenarios. Over the last two decades, chest computed tomography has been increasingly used for a wide variety of indications, including respiratory illnesses, trauma, oncologic staging, and more recently lung cancer screening. Diagnostic radiologists should be familiar with the common causes of missed lung cancers on imaging studies in order to avoid detection and interpretation errors. Failure to detect these lesions can potentially have serious implications for both patients as well as the interpreting radiologist.
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