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Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
Published on: October 24, 2018
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Long venous cannula on the arterial position for VA-ECMO
Maria L Rodriguez1, Gyaandeo Maharajh1
1Division of Pediatric Cardiovascular Surgery, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
Perfusion
|April 7, 2018
Summary
This study presents a novel bicaval drainage and retrograde extracorporeal membrane oxygenation (ECMO) flow technique. This approach aims to improve oxygen delivery to vital organs in pediatric patients requiring VA-ECMO support.
Area of Science:
- Cardiovascular Medicine
- Pediatric Critical Care
- Extracorporeal Life Support
Background:
- Managing peripheral veno-arterial extracorporeal membrane oxygenation (VA-ECMO) presents challenges including differential hypoxia and arterial deoxygenation.
- Optimizing oxygen delivery to the aortic arch branches and coronary arteries is crucial for patient outcomes.
Observation:
- A novel VA-ECMO cannulation strategy was developed.
- This technique involves bicaval drainage via the femoral vein and retrograde ECMO flow.
- A multi-stage venous cannula is inserted into the femoral artery, with its tip positioned in the proximal descending thoracic aorta.
Findings:
- The described VA-ECMO approach was successfully applied in two pediatric cases.
- A 15-year-old female with combined cardiorespiratory failure and a 12-year-old male with acute cardiac failure were treated.
- This method facilitates improved perfusion to the aortic arch and coronary arteries.
Implications:
- This cannulation technique offers a potential solution for improving cerebral and myocardial perfusion during peripheral VA-ECMO.
- It may enhance management strategies for pediatric patients with complex cardiorespiratory failure.
- Further research is warranted to validate the long-term efficacy and safety of this approach.
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