Related Experiment Video
Updated: Feb 12, 2026

A Swin Transformer-Based Model for Thyroid Nodule Detection in Ultrasound Images
Published on: April 21, 2023
Impact of oncogene panel results on surgical management of cytologically indeterminate thyroid nodules
Pablo Valderrabano1, Laila Khazai2, Zachary J Thompson3
1Department of Head and Neck-Endocrine Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
Background:
The impact of oncogene panel results on the surgical management of indeterminate thyroid nodules (ITNs) is currently unknown.
Methods:
Surgical management of 649 patients consecutively evaluated from October 2008 to April 2016 with a single nodule biopsied and indeterminate cytology (193 evaluated with and 456 without oncogene panels) was assessed and compared. Histological features of 629 consecutively resected ITNs (164 evaluated with and 465 without oncogene panels) were also characterized and compared.
Results:
Oncogene panel evaluation was associated with higher rates of total thyroidectomy (45% vs 28%; P = .006), and central lymph node dissection (19% vs 12%; P = .03) without increasing the yield of malignancy or decreasing the rate of completion thyroidectomy. Most malignancies (64%), including 83% of those with driver mutation identified, were low-risk cancers for which a lobectomy could have been sufficient initial treatment.
Conclusion:
Current oncogene panel results seem insufficient to guide the surgical extent of solitary ITNs.
More Related Videos
11:46Investigation of the Electrophysiological and Thermographic Safety Parameters of Surgical Energy Devices During Thyroid and Parathyroid Surgery in a Porcine Model
Published on: October 13, 2022
04:39Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
Related Concept Videos
Indeterminate Products
Indeterminate Structure
Urinary Tract Calculi VI: Surgical Management
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Statically Indeterminate Problem Solving
Wood Panel Products