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[Clinical assessment and diagnostic tools].

Pedro Gil Gregorio1

  • 1Servicio Geriatría, Hospital Clínico San Carlos, Madrid, España.

Revista Espanola De Geriatria Y Gerontologia
|April 10, 2018
PubMed
Summary
This summary is machine-generated.

Early identification of cognitive impairment is crucial for timely diagnosis, treatment, and planning. Research highlights the need for unified criteria and dynamic biomarkers for better assessment and understanding of cognitive frailty.

Keywords:
Biomarcadores dinámicosCognitive frailtyDynamic biomarkersFragilidad cognitivaNeuropsychological assessmentValoración neuropsicológica

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Area of Science:

  • Neurology
  • Gerontology
  • Psychiatry

Background:

  • Cognitive impairment significantly impacts individuals, families, and healthcare providers.
  • Early identification enables timely diagnosis, treatment, and planning for care and finances.
  • The scientific community shows great interest in age-related cognitive changes, necessitating unified criteria and longitudinal studies.

Purpose of the Study:

  • To emphasize the importance of early identification of cognitive impairment.
  • To discuss the role of diagnostic tools and biomarkers.
  • To explore the concept of cognitive frailty and its relation to physical frailty.

Main Methods:

  • Review of existing literature on cognitive impairment and its assessment.
  • Discussion of clinical assessment, including history-taking and neuropsychological testing.
  • Exploration of dynamic biomarkers (amyloidosis, neurodegeneration) and their time-dependent models.

Main Results:

  • A need exists to unify criteria and conduct longitudinal studies for reliable conclusions on cognitive alterations.
  • An ideal screening test should be brief and effective in identifying patients needing further assessment.
  • Dynamic biomarkers offer a promising approach for assessing cognitive changes over time.

Conclusions:

  • Cognitive status is an integral component of frailty syndrome.
  • Cognitive frailty, a parallel to physical frailty, affects a subgroup of patients with cognitive impairment, leading to functional decline.
  • Further research and unified approaches are essential for managing cognitive impairment and frailty effectively.