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Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
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Frailty in elderly people with chronic kidney disease
Maria Eugenia Portilla Franco1, Fernando Tornero Molina2, Pedro Gil Gregorio1
1Servicio de Geriatría, Hospital Clínico San Carlos, Madrid, España.
Summary
Frailty, a state of pre-disability common in older adults, is linked to poor health outcomes. Research explores the connection between frailty and chronic kidney disease in the elderly.
Area of Science:
- Gerontology
- Nephrology
- Public Health
Background:
- Frailty is a prevalent condition in older adults (over 25% in those >85 years), recognized as a significant risk factor for disability, institutionalization, and mortality.
- Chronic kidney disease (CKD) is associated with numerous adverse clinical outcomes, including cardiovascular disease, end-stage renal disease, infections, and functional decline.
- The interplay between aging, frailty, and CKD is a critical area of research, particularly given that frailty is potentially reversible.
Purpose of the Study:
- To review and synthesize recent scientific literature on the association between aging, frailty, and chronic kidney disease.
- To highlight the clinical relevance of studying frailty in elderly patients with CKD.
Main Methods:
- Systematic review of recent scientific publications.
- Analysis of epidemiological data and clinical studies on frailty and CKD.
Main Results:
- The prevalence of frailty increases with age and is exacerbated by conditions like CKD.
- CKD is an independent risk factor contributing to the development and progression of frailty.
- Evidence suggests that interventions targeting CKD may positively impact frailty status.
Conclusions:
- Frailty and CKD are interconnected conditions in the elderly, significantly increasing health risks.
- Understanding this association is crucial for developing effective management strategies and interventions.
- Further research is warranted to explore therapeutic approaches for mitigating frailty in CKD patients.
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