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Spinal infections in children: a multicentre retrospective study.

R Dayer1, M M Alzahrani2, N Saran3

  • 1Division of Paediatric Orthopaedics, University Hospitals of Geneva, 6 Rue Willy Donzé, 1211 Geneva 14, Switzerland.

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|April 10, 2018
PubMed
Summary

Primary pyogenic spinal infections in children are more common in males. Methicillin-sensitive Staphylococcus aureus (MSSA) and Kingella kingae are key pathogens, particularly in young children.

Keywords:
Kingella kingaeMulticentre retrospective studyPaediatric primary spine infections

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Area of Science:

  • Pediatric infectious diseases
  • Orthopedic surgery
  • Microbiology

Background:

  • Primary pyogenic spinal infections in children are rare but serious conditions.
  • Understanding epidemiological and etiological factors is crucial for effective management.

Purpose of the Study:

  • To enhance knowledge of pediatric primary pyogenic spinal infections.
  • To analyze a large consecutive case series for epidemiological and microbiological insights.

Main Methods:

  • Retrospective analysis of medical records from 103 children treated between 2004 and 2014.
  • Evaluation of epidemiological, clinical, paraclinical, radiological, and microbiological data.

Main Results:

  • A male predominance (65%) was observed.
  • The lumbar spine, particularly L4/5, was the most affected region.
  • Methicillin-sensitive Staphylococcus aureus (MSSA) and Kingella kingae were the most common pathogens.

Conclusions:

  • MSSA is a primary pathogen, while K. kingae is significant in children aged 6 months to 4 years.
  • Empirical antibiotic protocols should consider age distribution and specific bacteriology.
  • Further prospective studies are needed to validate findings and explore diagnostic tools like PCR for K. kingae.