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Published on: October 6, 2016
Failed Vacuum and the Long-term Hematologic Morbidity of the Offspring
Salvatore A Mastrolia1,2, Tamar Wainstock3, Eyal Sheiner1
1Department of Obstetrics and Gynecology, Soroka University Medical Center.
Insights
Failed vacuum delivery leading to cesarean birth does not increase long-term pediatric hematologic morbidity in offspring up to age 18. This study found no significant difference in blood disorders between successful and failed vacuum deliveries.
Area of Science:
- Obstetrics and Gynecology
- Pediatric Hematology
- Perinatal Medicine
Background:
- Vacuum-assisted delivery is a common obstetric procedure.
- Failed vacuum delivery may necessitate emergency cesarean birth, raising concerns about potential offspring health implications.
Purpose of the Study:
- To investigate the long-term risk of pediatric hematologic morbidity in children born after a failed vacuum delivery compared to successful vacuum delivery.
Main Methods:
- Population-based cohort study including 7978 neonates.
- Comparison of hematologic morbidity up to age 18 between successful (n=7733) and failed (n=245) vacuum deliveries.
- Kaplan-Meier survival analysis and Cox proportional hazards modeling were used to assess outcomes and control for confounders.
Main Results:
- Overall hematologic morbidity up to age 18 was similar between groups (1.6% vs. 0.8%, P=0.8).
- Kaplan-Meier analysis showed no significant difference in cumulative incidence of hematologic morbidity (log rank, P=0.22).
- Failed vacuum delivery was not independently associated with increased long-term hematologic morbidity after adjusting for confounders (aHR, 1.8; P=0.25).
Conclusions:
- Failed vacuum delivery followed by cesarean birth does not appear to elevate the risk of pediatric hematologic morbidity in offspring up to 18 years.
- These findings suggest that the mode of delivery, specifically failed vacuum extraction, is not a significant risk factor for long-term blood disorders in children.
Objective:
We aimed to investigate the effect of failed vacuum delivery leading to an emergency cesarean delivery on the long-term pediatric hematologic morbidity of the offspring.
Study Design:
In this population-based cohort study, the risk of long-term hematologic morbidity (up to the age of 18 y) was evaluated in children born following successful vacuum vaginal delivery, as compared with that of children born following a failed procedure leading to an emergent cesarean delivery. Multiple pregnancies and fetuses with congenital malformations were excluded. A Kaplan-Meier survival curve was constructed to compare cumulative pediatric hematologic morbidity, and a Cox proportional hazards model was used to control for confounders.
Results:
A total of 7978 neonates met the inclusion criteria. Vacuum delivery was successful in 7733 cases (96.9%), whereas it failed in 245 cases (3.1%). Total hematologic morbidity of the offspring up to 18 years of age was comparable between the groups (1.6% vs. 0.8%, P=0.8). The Kaplan-Meier survival curve showed no difference in the cumulative incidence of total hematologic morbidity (log rank, P=0.22). In the Cox regression model, failed vacuum delivery was not independently associated with long-term hematologic morbidity, as compared with a successful procedure, while adjusting for multiple confounders (adjusted hazards ratio [HR], 1.8; 95% confidence interval, 0.7-5.0; P=0.25).
Conclusions:
Failed vacuum delivery does not seem to be associated with an increased risk for pediatric hematologic morbidity of the offspring up to 18 years of age.
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