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Updated: Feb 12, 2026

A Preclinical Model of Exertional Heat Stroke in Mice
Published on: July 1, 2021
Exertional Dyspnea and Excessive Dynamic Airway Collapse
Michael J Morris1, Jeffrey T Woods1, Cameron W McLaughlin1
1Pulmonary/Critical Care Service (MCHE-ZMD-P), Department of Medicine, San Antonio Military Medical Center, 3551 Roger Brooke Drive, JBSA Fort Sam Houston, TX 78234, USA.
Abstract:
Excessive dynamic airway collapse is a relatively new diagnosis separate from tracheobronchomalacia that is manifested by functional collapse of the large airways. Most commonly described in patients with underlying obstructive lung disease such as chronic obstructive pulmonary disease and asthma, it may contribute to increased dyspnea, cough, or exacerbations. There are few data published on the role of excessive dynamic airway collapse as related specifically to exercise. It was recently described as the cause for exertional dyspnea in individuals without underlying lung disease.
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