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Gamma-3-MSH and beta-endorphin in monkey pituitary
J Meador-Woodruff1, M Knobloch, H Vaudry
1Mental Health Research Institute, University of Michigan Medical Center, Ann Arbor 48109-0720.
Abstract:
The content and extent of processing of gamma-3-MSH and beta-endorphin were determined in the anterior (AL) and intermediate (IL) lobes of three monkey pituitaries. The peptides existed in equimolar amounts in each lobe. The processing of gamma-3-MSH paralleled that of beta-endorphin in each lobe; the primary products in AL were beta-lipotropin and a 9K form of gamma MSH, whereas in IL the predominant products were N-acetyl-beta-endorphin and gamma-3-MSH.