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Updated: Feb 12, 2026

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Quality of Cardiovascular Disease Care in Small Urban Practices
Donna Shelley1, Batel Blechter2, Nina Siman2
1School of Medicine, New York University, New York, New York Donna.Shelley@nyumc.org.
Insights
Small primary care practices meet Million Hearts goals for cardiovascular health. However, managing patients with arteriosclerotic cardiovascular disease (ASCVD) risk factors requires more support, especially in solo practices.
Area of Science:
- Public Health
- Cardiovascular Medicine
- Primary Care Research
Background:
- Million Hearts initiative aims to improve cardiovascular health by focusing on ABCS (aspirin use, blood pressure control, cholesterol management, smoking screening/counseling).
- Performance measurement is crucial for assessing the effectiveness of primary care in managing cardiovascular disease risk factors.
Purpose of the Study:
- To evaluate the performance of small, independent primary care practices in meeting Million Hearts ABCS goals.
- To assess performance on a composite measure for patients with arteriosclerotic cardiovascular disease (ASCVD).
- To explore the relationship between practice characteristics and ABCS performance.
Main Methods:
- Cross-sectional analysis of baseline data from 134 New York City practices.
- ABCS data extracted from electronic health records.
- Practice characteristics collected via clinician and staff surveys.
Main Results:
- Performance varied across practices, with 73% for aspirin use, 69.6% for blood pressure, 66.7% for cholesterol, and 74.2% for smoking.
- Only 49% of ASCVD patients met all ABC targets (composite measure).
- Solo practices showed higher likelihood of meeting aspirin and composite guidelines compared to multi-clinician practices.
Conclusions:
- Small practices generally meet or exceed Million Hearts goals.
- Consistent achievement of clinical targets is lower for patients with ASCVD risk factors.
- Enhanced support is needed for small practices managing complex ASCVD patients.
Purpose:
We wanted to describe small, independent primary care practices' performance in meeting the Million Hearts ABCSs (aspirin use, blood pressure control, cholesterol management, and smoking screening and counseling), as well as on a composite measure that captured the extent to which multiple clinical targets are achieved for patients with a history of arteriosclerotic cardiovascular disease (ASCVD). We also explored relationships between practice characteristics and ABCS measures.
Methods:
We conducted a cross-sectional, bivariate analysis using baseline data from 134 practices in New York City. ABCS data were extracted from practices' electronic health records and aggregated to the site level. Practice characteristics were obtained from surveys of clinicians and staff at each practice.
Results:
The proportion of at-risk patients meeting clinical goals for each of the ABCS measures was 73.0% for aspirin use, 69.6% for blood pressure, 66.7% for cholesterol management, and 74.2% screened for smoking and counseled. For patients with a history of ASCVD, only 49% were meeting all ABC (aspirin use, blood pressure control, cholesterol management) targets (ie, composite measure). Solo practices were more likely to meet clinical guidelines for aspirin (risk ratio [RR] =1.17, P =.007) and composite (RR=1.29, P = .011) than practices with multiple clinicians.
Conclusion:
Achieving targets for ABCS measures varied considerably across practices; however, small practices were meeting or exceeding Million Hearts goals (ie, 70% or greater). Practices were less likely to meet consistently clinical targets that apply to patients with a history of ASCVD risk factors. Greater emphasis is needed on providing support for small practices to address the complexity of managing patients with multiple risk factors for primary and secondary ASCVD.
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Overview of the Cardiovascular System
Heart
The heart is the central pump of the cardiovascular system that circulates blood throughout the body. It comprises two atria receiving the blood and two ventricles pumping blood out of the heart. Their rhythmic contractions, called heartbeats, ensure that blood flow remains continuous.
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